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A microfluidic-based microwave interferometric inductance sensor capable of detecting single micron-size superparamagnetic particles in flow

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dc.contributor.supervisor Bridges, Greg (Electrical & Computer Engineering) en_US
dc.contributor.author Rzeszowski, Szymon
dc.date.accessioned 2012-09-19T15:06:20Z
dc.date.available 2012-09-19T15:06:20Z
dc.date.issued 2012-09-19
dc.identifier.uri http://hdl.handle.net/1993/8877
dc.description.abstract A microfluidic-based inductance sensor operating at 1.5 GHz is presented that can detect single 4.5 μm superparamagnetic particles flowing in a microfluidic channel. The particles are detected as they pass over a micron-sized planar gold loop electrode, with a maximum signal-to-noise ratio of 26.3 dB for an 80 μm/s flow rate; the magnetic beads are simultaneously observed with microscope images. The sensor consists of a coupled-line resonator and microwave interferometric system coupled to the loop electrode that is integrated within a polydimethylsiloxane-on-glass microfluidic chip assembly. A time-averaged inductance change caused by a single particle is related to the real part of its magnetic Clausius-Mossotti factor. The effective real part of the magnetic permeability for a particular particle is estimated to be 1.13 at 1.5 GHz. The sensor detects magnetic particles in flow and does not require an external biasing magnetic field, which distinguishes it from other magnetic microparticle sensors. en_US
dc.rights info:eu-repo/semantics/openAccess
dc.subject Inductance en_US
dc.subject Sensor en_US
dc.subject Microfluidics en_US
dc.subject Superparamagnetic en_US
dc.subject Microwave en_US
dc.title A microfluidic-based microwave interferometric inductance sensor capable of detecting single micron-size superparamagnetic particles in flow en_US
dc.type info:eu-repo/semantics/masterThesis
dc.type master thesis en_US
dc.degree.discipline Electrical and Computer Engineering en_US
dc.contributor.examiningcommittee Oliver, Derek (Electrical & Computer Engineering) Hu, Can-Ming (Physics and Astronomy) en_US
dc.degree.level Master of Science (M.Sc.) en_US
dc.description.note October 2012 en_US


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