Melanoma arises from melanocytes in the skin (cutaneous) or mucosa (mucosal). It is one of the most aggressive skin cancers when compared to other, non-melanoma skin cancers. Worldwide, melanoma represents 4% of all skin ...

Concussion is a complex pathophysiological process affecting the brain, induced by traumatic biomechanical forces. From 2005 to 2010, approximately 7,000 Manitobans aged 14-18 years were diagnosed with a concussion. About ...

Hydrocephalus causes damage to periventricular white matter via compression, stretching, waste material accumulation, and ischemia. Nimodipine has been shown to provide benefits clinically in subarachnoid hemorrhage and ...

Trigeminal neuralgia (TN) is regarded as one of the most painful conditions afflicting humans. It is a relatively rare disease with an estimated incidence of 4/1 00,000/year. While TN progresses in severity over time, ...

Pediatric medical traumatic stress (PMTS) has been defined as “a set of psychological and physiological responses of children and their families to pain, injury, serious illness, medical procedures, and invasive or frightening ...

Cisplatin is an effective antineoplastic drug which is often limited in it‘s use by an ototoxic side effect. After cisplatin enters the cochlea, a large amount reactive oxygen species (ROS) is generated. This large production ...

Background: Extracorporeal membrane oxygenation (ECMO) to treat severe cardiorespiratory illness has seen a marked increased in the last decade. Much of the data regarding this intensive therapy is short term in nature ...

A concussion is a complex pathophysiological process affecting the brain, which can result from traumatic biomechanical forces, often occurring in youth while playing sports. Symptoms include headache, dizziness, nausea, ...