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Extent of Resection in Glioblastoma: Incorporating IDH Status and Clinical Factors to Predict Outcome
(2017-08-03)
Background: The benefits of increasing extent of resection (EOR) for both overall survival and progression-free
survival(PFS) in glioblastoma has been well documented. However, models predicting surgical outcomes have ...
Biceps Tenodesis versus Tenotomy in the Treatment of Lesions of the Long Head of Biceps Brachii : Randomized Clinical Trial - An Interim Analysis
(2014-08-08)
Background: Both biceps tenotomy and tenodesis have been shown to produce comparable, effective results in treatment of lesions of the long head of biceps tendon (LHBT). The aim of this study was to provide an interim ...
Cognitive Impairment in Advanced CKD: The Canadian Frailty Observation and Interventions Trial (CanFIT)
(2015-08-07)
Chronic kidney disease (CKD) is a major public health problem with increasing incidence and prevalence in North America and worldwide.
CKD disproportionately affects the elderly, and leads to higher risks of kidney failure, ...
The utility of a brief large group psychoeducational program for patients waiting for cognitive-behavioural treatment of anxiety
(2018-08-23)
Anxiety disorders are very common and are characterized by feelings of excessive fear that disrupt quality of life (Kampman, Viikki, & Leinonen, 2017). The symptoms of anxiety (e.g. palpitations, racing thoughts, and ...
Avastin, Sutent and Votrient induced cardiotoxicity Study (ASICS): Early detection of Bevacizumab and Sunitinib mediated cardiotoxicity in cancer patients:
(2016)
Cancer is a significant health concern in Canada, where it is expected that approximately 2 in 5 Canadians will develop cancer during their lifetime. Although current anti-cancer therapies may be effective in leading ...
Chemoradiosensitization of Malignant Glioma through Co-inhibition of Redundant DNA Repair Pathways
(2015-08-07)
The objective of common front-line radiation and chemotherapeutic strategies
used in the treatment of brain tumours is to induce DNA breaks and overwhelm
the cellular DNA repair machinery thus promoting genomic damage ...
The relationship between active proteolytic enzymes and intraluminal thrombus in human abdominal aortic aneurysms
(2018-08-23)
We have previously shown that the region of abdominal aortic aneurysms (AAA) containing intraluminal thrombus may be at higher risk of rupture. The purpose of this study is to evaluate differential expression of macrophage ...
Person and place in perinatal outcomes: how the interaction between rural residence and Aboriginal heritage alters birth outcomes
(2015-08-07)
The provision of intrapartum health care in rural and remote Canadian communities is declining, due to a shortage of family physicians, obstetricians, nurses and midwives, and due to the centralization of such services to ...
Frailty affects treatment decisions and outcomes for patients with chronic kidney disease
(2016)
Chronic kidney disease (CKD) is a major public health problem with increasing incidence and prevalence in North America and worldwide. CKD disproportionately affects the elderly, and leads higher risks of kidney failure, ...