Cisplatin is an effective antineoplastic drug which is often limited in it‘s use by an ototoxic side effect. After cisplatin enters the cochlea, a large amount reactive oxygen species (ROS) is generated. This large production ...

Epithelial ovarian cancer (EOC) is the most lethal form of gynecological cancer. EOC patients have a low survival rate primarily due to the late stage at which the disease is diagnosed (typically after metastasis), and ...

Background: The current surgical training model is based primarily on cadaveric dissection; however, opportunities are limited due to small numbers of specimens. Alternatives to cadaveric dissection such as virtual reality ...

Background: Extracorporeal membrane oxygenation (ECMO) to treat severe cardiorespiratory illness has seen a marked increased in the last decade. Much of the data regarding this intensive therapy is short term in nature ...

A concussion is a complex pathophysiological process affecting the brain, which can result from traumatic biomechanical forces, often occurring in youth while playing sports. Symptoms include headache, dizziness, nausea, ...

Intraoperative femur fracture is a common complication that arises during cementless total hip arthroplasty (THA) likely due to the strain applied to the bone to achieve a press-fit. These fractures occur with a prevalence ...

A recent population-based study in Manitoba showed that skin cancers are very common in chronic lymphocytic leukemia (CLL), probably as a result of immunosuppression. We have now studied 592 newly diagnosed CLL patients ...

Anti-scatter grids represent an important way of improving image quality in x-ray based exams. However, their use comes with increased radiation dosages. Removing anti-scatter grids represents a potential way to limit ...