Correlates of aspiration and lower respiratory tract infection in children
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Rationale: Lower respiratory tract infections (LRTI) are a common cause of morbidity and mortality in children. Swallowing problems are also common in children. Aspiration is one outcome of swallowing dysfunction that may be a contributing factor to LRTI. Methods: Retrospective review of children undergoing videofluoroscopic swallow study was done to identify the prevalence and correlates of aspiration and LRTI. Results: Aspiration prevalence was 36.6%. Significant factors on univariate analysis included: developmental delay, LRTI, pneumonia, digestive tract anomalies, indigenous heritage, cough and congestion. With logistic regression, congestion and LRTI correlated with aspiration. Prevalence of LRTI was 42%. Using univariate analysis pneumonia, aspiration and indigenous heritage were significant. With logistic regression, respiratory issues and indigenous heritage correlated with LRTI. Conclusion: The etiology of LRTI is complex and multifactoral. Understanding the relationship between all factors is imperative given that current interventions are invasive and the untreated outcome can be progressive lung injury.