Fast simulation of finite-beam optical coherence tomography of inhomogeneous turbid media

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Date
2018-10-09
Authors
Sobhy, Micheal Ramez Wadee
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Abstract
We developed a fast simulator of finite-beam optical coherence tomography (OCT) of inhomogeneous turbid media. Our Sequential Monte Carlo (MC) based finite beam OCT simulator can reach more than a hundred times faster than one that represents a finite OCT’s incident beam as a superposition of infinitely thin beams, i.e., a superposition-based MC simulator. In this thesis, first, we highlight the lesser-known correspondence between the commonly used MC simulation of light in turbid media, and Sequential MC based solution of the Radiative Transfer Equation (RTE). Second, we describe the implementation of our simulator of finite-beam OCT as a Sequential MC solution to the RTE. Third, we derive analytical expressions for the relationship between simulation errors and computational complexities, i.e., simulation times, for both our Sequential MC based simulator and a superposition-based MC simulator. We present simulation results of finite beam OCT of inhomogeneous turbid media when having a finite beam with a Gaussian intensity profile. Our simulator could be used in OCT design since it models realistic beam profiles that are typically used in OCT systems.
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Keywords
Optical Coherence Tomography, Light Simulation in tissue
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