Antihyperglycemic Effects of Short Term Resveratrol Supplementation in Type 2 Diabetic Patients

Simple item page
dc.contributor.authorMovahed, Ali
dc.contributor.authorNabipour, Iraj
dc.contributor.authorLieben Louis, Xavier
dc.contributor.authorThandapilly, Sijo Joseph
dc.contributor.authorYu, Liping
dc.contributor.authorKalantarhormozi, Mohammadreza
dc.contributor.authorRekabpour, Seyed Javad
dc.contributor.authorNetticadan, Thomas
dc.date.accessioned2014-08-14T06:47:33Z
dc.date.available2014-08-14T06:47:33Z
dc.date.issued2013-9-1
dc.date.updated2014-08-14T06:47:33Z
dc.description.abstractThe objective of this study was to examine the effectiveness of resveratrol in lowering blood glucose in the presence of standard antidiabetic treatment in patients with type 2 diabetes, in a randomized placebo-controlled double-blinded parallel clinical trial. A total of 66 subjects with type 2 diabetes were enrolled in this study and randomly assigned to intervention group which was supplemented with resveratrol at a dose 1 g/day for 45 days and control group which received placebo tablets. Body weight, blood pressure, fasting blood glucose, haemoglobin A1c, insulin, homeostatic assessments for insulin resistance, triglycerides, total cholesterol, low density lipoprotein, high density lipoprotein, and markers of liver and kidney damage were measured at baseline and after 45 days of resveratrol or placebo supplementation. Resveratrol treatment significantly decreased systolic blood pressure, fasting blood glucose, haemoglobin A1c, insulin, and insulin resistance, while HDL was significantly increased, when compared to their baseline levels. On the other hand, the placebo group had slightly increased fasting glucose and LDL when compared to their baseline levels. Liver and kidney function markers were unchanged in the intervention group. Overall, this study showed that resveratrol supplementation exerted strong antidiabetic effects in patients with type 2 diabetes.
dc.description.versionPeer Reviewed
dc.identifier.citationAli Movahed, Iraj Nabipour, Xavier Lieben Louis, et al., “Antihyperglycemic Effects of Short Term Resveratrol Supplementation in Type 2 Diabetic Patients,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 851267, 11 pages, 2013. doi:10.1155/2013/851267
dc.identifier.doihttp://dx.doi.org/10.1155/2013/851267
dc.identifier.urihttp://hdl.handle.net/1993/23769
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderCopyright © 2013 Ali Movahed et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.titleAntihyperglycemic Effects of Short Term Resveratrol Supplementation in Type 2 Diabetic Patients
dc.typeJournal Article
Files
Original bundle
Now showing 1 - 2 of 2
Thumbnail Image
Name:
ECAM.2013.851267.xml
Size:
10.61 KB
Format:
Extensible Markup Language
Description:
Download
Thumbnail Image
Name:
ECAM.2013.851267.pdf
Size:
988.08 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
2.17 KB
Format:
Item-specific license agreed to upon submission
Description:
Download
Collections
University of Manitoba Scholarship
Rady Faculty of Health Sciences Scholarly Works