Rail and industrial operations pose significant environmental and safety risks. This study conducted a spatial analysis of these risks in Point Douglas and South St. Boniface, Winnipeg, Canada. Using ArcGIS, the rail network, industrial sites, and land uses in these areas were mapped, with a focus on the proximity of rail lines and industrial sites to vulnerable land uses. The analysis identified populations at risk from potential hazards such as fires, spills, or train derailments involving dangerous goods, which may require evacuation or isolation. The findings underscore the need for mitigation strategies and policy interventions to reduce environmental and safety risks in these communities.