Effect of high frequency TENS on cold hyperalgesia induced by topical menthol in healthy subjects

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dc.contributor.authorIribarren, Onae
dc.contributor.examiningcommitteeMacNeil, Brian (Physical Therapy) Shay, Barbara (Physical Therapy) Shefchyk, Susan (Physiology)en_US
dc.contributor.supervisorMacNeil, Brian (Physical Therapy)en_US
dc.date.accessioned2011-09-27T15:24:28Z
dc.date.available2011-09-27T15:24:28Z
dc.date.issued2011-09-27
dc.degree.disciplineMedical Rehabilitationen_US
dc.degree.levelMaster of Science (M.Sc.)en_US
dc.description.abstractThe primary aim of this study was to determine the effect of high frequency Transcutaneous Electrical Nerve Stimulation (TENS) on cold sensory function following topical application of menthol. Quantitative sensory testing was used to determine cold sensation and cold pain thresholds before and after topical application of a 40% menthol solution in 9 male and 11 female subjects. In a separate session the effect of TENS (100 HZ, constant pulse, 100µs, 20 minutes) was determined on menthol-induced cold sensation. Menthol produced a distinct cold hyperalgesia which was significantly reduced during the application of high frequency TENS. The analgesic effect of TENS persisted beyond the application period for at least 20 minutes. Menthol also reduced cold detection thresholds but TENS had no effect on this aspect of cold sensation. These data support the use of TENS as a means of treating cold hyperalgesia such as that found in neuropathic pain states.en_US
dc.description.noteOctober 2011en_US
dc.identifier.urihttp://hdl.handle.net/1993/4940
dc.language.isoengen_US
dc.rightsopen accessen_US
dc.subjectTENSen_US
dc.subjectMentholen_US
dc.subjectQSTen_US
dc.subjectcold hyperalgesiaen_US
dc.titleEffect of high frequency TENS on cold hyperalgesia induced by topical menthol in healthy subjectsen_US
dc.typemaster thesisen_US
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