Clinical Practice Guidelines for Hospital-Acquired Pneumonia and Ventilator-Associated Pneumonia in Adults

dc.contributor.authorRotstein, Coleman
dc.contributor.authorEvans, Gerald
dc.contributor.authorBorn, Abraham
dc.contributor.authorGrossman, Ronald
dc.contributor.authorLight, R Bruce
dc.contributor.authorMagder, Sheldon
dc.contributor.authorMcTaggart, Barrie
dc.contributor.authorWeiss, Karl
dc.contributor.authorZhanel, George G
dc.date.accessioned2016-06-08T16:40:02Z
dc.date.available2016-06-08T16:40:02Z
dc.date.issued2008-1-1
dc.date.updated2016-06-07T06:58:11Z
dc.description.abstractHospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) are important causes of morbidity and mortality, with mortality rates approaching 62%. HAP and VAP are the second most common cause of nosocomial infection overall, but are the most common cause documented in the intensive care unit setting. In addition, HAP and VAP produce the highest mortality associated with nosocomial infection. As a result, evidence-based guidelines were prepared detailing the epidemiology, microbial etiology, risk factors and clinical manifestations of HAP and VAP. Furthermore, an approach based on the available data, expert opinion and current practice for the provision of care within the Canadian health care system was used to determine risk stratification schemas to enable appropriate diagnosis, antimicrobial management and nonantimicrobial management of HAP and VAP. Finally, prevention and risk-reduction strategies to reduce the risk of acquiring these infections were collated. Future initiatives to enhance more rapid diagnosis and to effect better treatment for resistant pathogens are necessary to reduce morbidity and improve survival.
dc.description.versionPeer Reviewed
dc.identifier.citationColeman Rotstein, Gerald Evans, Abraham Born, et al., “Clinical Practice Guidelines for Hospital-Acquired Pneumonia and Ventilator-Associated Pneumonia in Adults,” Canadian Journal of Infectious Diseases and Medical Microbiology, vol. 19, no. 1, pp. 19-53, 2008. doi:10.1155/2008/593289
dc.identifier.urihttp://dx.doi.org/10.1155/2008/593289
dc.identifier.urihttp://hdl.handle.net/1993/31394
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderCopyright © 2008 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.titleClinical Practice Guidelines for Hospital-Acquired Pneumonia and Ventilator-Associated Pneumonia in Adults
dc.typeJournal Article
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