Chemical disinfectant resistance in multiple antibiotic resistant and susceptible bacteria

dc.contributor.authorSuarez, Rachelen_US
dc.date.accessioned2007-05-22T15:12:20Z
dc.date.available2007-05-22T15:12:20Z
dc.date.issued2001-03-01T00:00:00Zen_US
dc.degree.disciplineMedical Microbiologyen_US
dc.degree.levelMaster of Science (M.Sc.)en_US
dc.description.abstractChemical disinfectants are used extensively in hospitals and other health care settings for a variety of hard-surface applications. The widespread use of chemical disinfectants has prompted some speculation that there may be a link between disinfectant resistance and antibiotic resistance. This type of link could have significant implications regarding nosocomial infections. The aim of the study was to evaluate whether such a link exists in bacterial strains that have been responsible for hospital outbreaks. We acquired several different bacterial species that were resistant to multiple antibiotics and had caused severe nosocomial outbreaks. These were compared to counterparts of the same species that were antibiotic susceptible strains. The comparison was performed using surface carrier as well as suspension testing. Because patient secretions may protect survival of organisms in the hospital setting, we incorporated an organic challenge in our test model. Our data for surface carrier and suspension tests indicated that even in the presence of an organic challenge, the multiple antibiotic resistant pathogens were not any more resistant to disinfectant killing compared to susceptible strains of the same species. (Abstract shortened by UMI.)en_US
dc.format.extent9093711 bytes
dc.format.extent184 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.identifier.urihttp://hdl.handle.net/1993/1995
dc.language.isoengen_US
dc.rightsopen accessen_US
dc.titleChemical disinfectant resistance in multiple antibiotic resistant and susceptible bacteriaen_US
dc.typemaster thesisen_US
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