Effects of “foods for health” portfolio of functional food products on lipid management in individuals unwilling to use statin therapy
| dc.contributor.author | Soumya, Alias | |
| dc.contributor.examiningcommittee | Dr. James House (Food and Human Nutritional Sciences), Dr. Michel Aliani ( Food and Human Nutritional Sciences), Dr. Todd Duhamel (Kinesiology and Recreation Management ) | en_US |
| dc.contributor.supervisor | Dr. James House (Department of Food and Human Nutritional Sciences) | en_US |
| dc.date.accessioned | 2019-04-25T13:46:14Z | |
| dc.date.available | 2019-04-25T13:46:14Z | |
| dc.date.issued | 2018 | en_US |
| dc.date.submitted | 2019-01-24T19:58:05Z | en |
| dc.degree.discipline | Human Nutritional Sciences | en_US |
| dc.degree.level | Master of Science (M.Sc.) | en_US |
| dc.description.abstract | The objective of this study was to examine the effect of a range of proprietary products containing a portfolio of bioactives (5 g fiber, 1000 mg alpha-linolenic acid, 1000 mg phytosterols and 1800 μmol antioxidants per serving), on cholesterol levels, in statin reluctant participants. A dual-center, randomized, double-blind, free-living cross-over study composed of 2 phases of 4 weeks each, separated by a 4 week washout, was conducted. Participants (n=54) consumed two servings per day from an assortment of products including oatmeal, pancakes, bars, sprinkles, and smoothies. Control products were market drawn like-items. Lipid profile, glucose, insulin and high sensitivity C-reactive protein concentrations were analyzed at baseline and endpoint of both phases. After consumption of study foods, in comparison to control foods, there were significant reductions in total cholesterol (5.08±8.24% or -0.28±0.47 mmol/l) and LDL-C levels (8.80±12.5% or -0.29±0.39 mmol/l) observed at endpoint. There were no significant changes in any other outcome. | en_US |
| dc.description.note | May 2019 | en_US |
| dc.identifier.uri | http://hdl.handle.net/1993/33864 | |
| dc.language.iso | eng | en_US |
| dc.rights | open access | en_US |
| dc.subject | Cardiovascular, phytosterol, fiber, Alpha linolenic acid | en_US |
| dc.title | Effects of “foods for health” portfolio of functional food products on lipid management in individuals unwilling to use statin therapy | en_US |
| dc.type | master thesis | en_US |