Browsing Rady Faculty of Health Sciences by Title
Now showing items 21-40 of 1639
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A Critical Review of Oxazolidinones: An Alternative or Replacement for Glycopeptides and Streptogramins?
(2001-1-1)OBJECTIVE: To review the available data on the oxazolidinones linezolid and eperezolid.DATA SELECTION: Published reports were obtained by searching MEDLINE for articles published between 1992 and 2000, inclusive. References ... -
A cross-sectional study evaluating cardiovascular risk and statin prescribing in the Canadian Primary Care Sentinel Surveillance Network database
(2022-05-25)Abstract Background Cardiovascular disease (CVD) is a major cause of morbidity and mortality in Canada. Assessment and management of CVD risk is essential in reducing disease ... -
A deep neural network based regression model for triglyceride concentrations prediction using epigenome-wide DNA methylation profiles
(2018-09-17)Abstract Background Epigenetic modification has an effect on gene expression under the environmental alteration, but it does not change corresponding genome sequence. DNA ... -
A descriptive qualitative examination of knowledge translation practice among health researchers in Manitoba, Canada
(2017-09-06)Abstract Background The importance of effective translation of health research findings into action has been well recognized, but there is evidence to suggest that the practice ... -
A Descriptive Study of Human Salmonella Serotype Typhimurium Infections Reported in Ontario from 1990 to 1997
(2003-1-1)BACKGROUND: Salmonella infections cause gastrointestinal and systemic diseases worldwide and are the leading causes of food-borne illnesses in North America (1-4). Salmonella serotype typhimurium (ST), in particular, is ... -
A Dutch Fanconi Anemia FANCC Founder Mutation in Canadian Manitoba Mennonites
(2012-6-4)Fanconi anemia (FA) is a recessive DNA instability disorder associated with developmental abnormalities, bone marrow failure, and a predisposition to cancer. Based on their sensitivity to DNA cross-linking agents, FA cells ... -
A generalizable pre-clinical research approach for orphan disease therapy
(2012-06-15)AbstractWith the advent of next-generation DNA sequencing, the pace of inherited orphan disease gene identification has increased dramatically, a situation that will continue for at least the next several years. At present, ... -
A Kenyan newspaper analysis of the limitations of voluntary medical male circumcision and the importance of sustained condom use
(2012-06-21)Abstract Background Since the completion of three clinical trials indicating that voluntary medical male circumcision (VMMC) is an effective method to reduce men’s chances of acquiring HIV, ... -
A machine learning-based clinical tool for diagnosing myopathy using multi-cohort microarray expression profiles
(2020-11-30)Abstract Background Myopathies are a heterogenous collection of disorders characterized by dysfunction of skeletal muscle. In practice, myopathies are frequently encountered by physicians and precise diagnosis remains a ... -
A mixed methods investigation of the relationship between blood donor policy, interest in donation, and willingness to donate among gay, bisexual, and other men who have sex with men in Ontario, Canada
(2022-04-28)Abstract Background As of 2019, men who have sex with men (MSM) in Canada are ineligible to donate blood if they have had oral or anal sex with another man in the last 3 months. ... -
A multicenter retrospective study of heterogeneous tissue aggregates obstructing ventricular catheters explanted from patients with hydrocephalus
(2021-07-21)Abstract Background Implantation of ventricular catheters (VCs) to drain cerebrospinal fluid (CSF) is a standard approach to treat hydrocephalus. VCs fail frequently due to ... -
A multiple case study of intersectoral public health networks: experiences and benefits of using research
(2016-02-11)Abstract Background Network partnerships between public health and third sector organisations are being used to address the complexities of population level social determinants ... -
A narrative review of gaps in the provision of integrated care for noncommunicable diseases in India
(2020-05-13)Abstract Background Low- and middle-income countries (LMICs) account for a higher burden of noncommunicable diseases (NCD) and home to a higher number of premature deaths ... -
A National Consensus Forum on improving cornea donation and transplantation access in Canada
(2021-05-11)Abstract A consensus meeting was held in Toronto on February 9–10, 2020 to discuss ways to improve cornea donation and transplantation access in Canada. The meeting brought together eye and tissue bank ... -
A novel CCBE1 mutation leading to a mild form of hennekam syndrome: case report and review of the literature
(2015-04-30)Abstract Background Mutations in CCBE1 have been found to be responsible for a subset of families with autosomal recessive Hennekam syndrome. Hennekam syndrome is defined as ... -
A novel HIV vaccine targeting the protease cleavage sites
(2017-09-12)Abstract HIV preferentially infects activated CD4+ T cells and mutates rapidly. The classical vaccine approach aimed to generate broad immune responses to full HIV proteins largely failed to address the ... -
A novel preference-informed complementary trial (PICT) design for clinical trial research influenced by strong patient preferences
(2021-03-12)Abstract Background Patients and their families often have preferences for medical care that relate to wider considerations beyond the clinical effectiveness of the proposed ... -
A novel strain of cynomolgus macaque cytomegalovirus: implications for host-virus co-evolution
(2016-04-05)Abstract Background Cytomegaloviruses belong to a large, ancient, genus of DNA viruses comprised of a wide array of species-specific strains that occur in diverse array of ... -
A pilot evaluation of the Strengthening a Palliative Approach in Long-Term Care (SPA-LTC) program
(2020-07-13)Abstract Background Despite increased annual mortality in long-term care (LTC) homes, research has shown that care of dying residents and their families is currently suboptimal in these settings. The purpose of this study ...