Browsing Rady Faculty of Health Sciences by Title
Now showing items 699-718 of 1640
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Garlic extracts prevent oxidative stress, hypertrophy and apoptosis in cardiomyocytes: a role for nitric oxide and hydrogen sulfide
(2012-08-29)Abstract Background In ancient times, plants were recognized for their medicinal properties. Later, the arrival of synthetic drugs pushed it to the backstage. However, from being merely ... -
Gastrointestinal and genitourinary toxicity profiles of metformin versus placebo in men with prostate cancer receiving prostate radiotherapy: interim toxicity results of a double-blinded, multicenter, phase II randomized controlled trial
(2021-11-04)Abstract Androgen deprivation therapy (ADT) used for prostate cancer (PCa) management is associated with metabolic and anthropometric toxicity. Metformin given concurrent to ADT is hypothesized to counteract ... -
Gastrointestinal symptoms before and during menses in healthy women
(2014-01-22)Abstract Background Little is known as to the extent gastrointestinal (GI) complaints are reported by women around menses. We aimed to describe GI symptoms that occurred premenstrually and ... -
Gefitinib as a Potential Treatment for Aggressive CLL
(2012-03-12)Chronic lymphocytic leukemia (CLL) is presently an incurable disease that is expected to increase in prevalence, as a result of the aging population. Currently, the standard treatment used is chlorambucil or fludarabine, ... -
Gender differences among Indigenous Canadians experiencing homelessness and mental illness
(2019-08-28)Abstract Background Indigenous people are over represented among homeless populations worldwide and the prevalence of Indigenous homelessness appears to be increasing in ... -
Gender-specific profiles of tobacco use among non-institutionalized people with serious mental illness
(2010-11-30)Abstract Background In many countries, smoking remains the leading preventable cause of death. In North America, reductions in population smoking levels are stabilising and, in recent years, those involved in tobacco control ... -
Genes and functions from breast cancer signatures
(2018-04-27)Abstract Background Breast cancer is a heterogeneous disease and personalized medicine is the hope for the improvement of the clinical outcome. Multi-gene signatures for breast ... -
Genome-wide gene expression profiling of stress response in a spinal cord clip compression injury model
(2013-08-28)Abstract Background The aneurysm clip impact-compression model of spinal cord injury (SCI) is a standard injury model in animals that closely mimics the primary mechanism of most human injuries: ... -
Genotyping an immunodeficiency causing c.1624–11G>A ZAP70 mutation in Canadian Mennonites
(2016-07-22)Abstract Background Primary immunodeficiency is a life-threatening genetic disease that appeared to have an increased incidence in Manitoba Mennonites. Determining the genetic ... -
Geographic and facility-level variation in the use of peritoneal dialysis in Canada: a cohort study
(CMA, 2014)Background Peritoneal dialysis is associated with similar survival and similar improvement in quality of life and is less costly compared with in-centre hemodialysis. We examined facility and geographic variation in the ... -
Geographical variation analysis of all-cause hospital readmission cases in Winnipeg, Canada
(2015-04-01)Abstract Background Hospital readmission is costly and potentially avoidable. The concept of virtual wards as a new model of care is intended to reduce hospital readmissions ... -
Germline mosaicism in X-linked periventricular nodular heterotopia
(2014-06-07)Abstract Background X-linked periventricular nodular heterotopia is a disorder of neuronal migration resulting from mutations in the filamin A gene. This is an X-linked dominant condition ... -
Gestational diabetes and barriers to care that may be addressed by physician assistants
(2020)Background – Gestational diabetes mellitus (GDM) is an increasingly common pregnancy complication. It occurs when women not previously diagnosed with diabetes mellitus develop high blood sugar during their pregnancy, ... -
Glia and TRPM2 Channels in Plasticity of Central Nervous System and Alzheimer’s Diseases
(2016-1-28)Synaptic plasticity refers to the ability of neurons to strengthen or weaken synaptic efficacy in response to activity and is the basis for learning and memory. Glial cells communicate with neurons and in this way contribute ... -
Glia maturation factor gamma regulates the migration and adherence of human T lymphocytes
(2012-04-18)AbstractBackgroundLymphocyte migration and chemotaxis are essential for effective immune surveillance. A critical aspect of migration is cell polarization and the extension of pseudopodia in the direction of movement. ... -
Glycopeptide heteroresistance in coagulase-negative Staphylococci: clinical implications, risk factors, and surveillance
(2016)Coagulase-negative staphylococci (CoNS) have been identified as the leading cause of late-onset sepsis in neonatal intensive care units (NICUs), resulting in poorer developmental outcomes and significant comorbidities. ... -
Gonadectomy in Mito-Ob mice revealed a sex-dimorphic relationship between prohibitin and sex steroids in adipose tissue biology and glucose homeostasis
(2018-08-29)Abstract Background Recently, we have developed a novel transgenic mouse model by overexpressing prohibitin (PHB) in adipocytes, which developed obesity due to upregulation ... -
Governance, maternal well-being and early childhood caries in 3–5-year-old children
(2020-06-05)Abstract Background This study assessed the direct, indirect and total effect of distal – political - risk indicators (affecting populations), and proximal risk indicators (affecting women) on the global prevalence of ... -
Granulomatous Pneumocystis Jiroveci Pneumonia Associated with Immune Reconstituted HIV
(2011-1-1)Pneumocystis jiroveci pneumonia uncommonly presents with pulmonary nodules and granulomatous inflammation. An unusual case of granulomatous P jiroveci pneumonia in an HIV patient with a CD4+ lymphocyte count of greater ... -
Ground truth labels challenge the validity of sepsis consensus definitions in critical illness
(2022-01-15)Abstract Background Sepsis is the leading cause of death in the intensive care unit (ICU). Expediting its diagnosis, largely determined by clinical assessment, improves survival. ...