Cell-compatible multi-functional crosslinker-based hydrogels for tissue engineering
Loading...
Date
2015-01-08
Authors
Yu, Lianlian Jr
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
The thesis showed preliminary evaluation of novel biodegradable and biocompatible agmatine-containing PAA crosslinkers. Hydrogels fabricated by this crosslinker can obtain controllable stiffness and excellent cell adhesion. The PAA contained thermo-sensitive hydrogel reported here is first employed as filler for depressed defects in rats. Results showed that such hydrogel can be injectable and biocompatible, might become a new material in plastic surgery in the clinic. The thesis also demonstrated a novel macro gels with self-healing capability and biocompatibility. The reversible photodimerization and photocleavage reactivity of coumarin has been successfully imparted to the polymer.
Description
Keywords
biocompatible, self-healing, hydrogel, crosslinker