Browsing University of Manitoba Scholarship by Author "Unruh, Helmut"

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    • Endogenous laminin is required for human airway smooth muscle cell maturation 

      Tran, Thai; McNeill, Karol D; Gerthoffer, William T; Unruh, Helmut; Halayko, Andrew J (2006-09-12)
      Abstract Background Airway smooth muscle (ASM) contraction underlies acute bronchospasm in asthma. ASM cells can switch between a synthetic-proliferative phenotype and a ...

    • Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts 

      Schaafsma, Dedmer; McNeill, Karol D; Mutawe, Mark M; Ghavami, Saeid; Unruh, Helmut; Jacques, Eric; Laviolette, Michel; Chakir, Jamila; Halayko, Andrew J (2011-08-24)
      Abstract Background Bronchial fibroblasts contribute to airway remodelling, including airway wall fibrosis. Transforming growth factor (TGF)-β1 plays a major role in this ...