Browsing University of Manitoba Scholarship by Author "Yang, Chengbo"
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Bacillus licheniformis PF9 improves barrier function and alleviates inflammatory responses against enterotoxigenic Escherichia coli F4 infection in the porcine intestinal epithelial cells
Li, Qiao; Li, Linyan; Chen, Yanhong; Yu, Changning; Azevedo, Paula; Gong, Joshua; Yang, Chengbo (2022-07-08)Abstract Background Enterotoxigenic Escherichia coli (ETEC) F4 commonly colonizes the small intestine and releases enterotoxins that impair the intestinal barrier function and ... -
Calcium-sensing Receptor is not Expressed in the Absorptive Enterocytes of Weaned Piglets
Zhao, Xiaoya; Hui, Qianqu; Azevedo, Paula A; Nyachoti, Charles M.; O, Karmin; Yang, Chengbo (2022-03-16)The calcium-sensing receptor (CaSR) is a kokumi receptor that plays an essential role in nutrient sensing and animal physiology, growth, and development. Pig CaSR (pCaSR) was identified and characterized in the intestine. ... -
Development of novel microparticles for effective delivery of thymol and lauric acid to pig intestinal tract
Omonijo, Faith; Kim, Seungil; Guo, Tracy; Wang, Qi; Gong, Joshua; Lahaye, Ludovic; Bodin, Jean-Christophe; Nyachoti, Martin; Liu, Song; Yang, Chengbo (2018-08-24)Antibiotics have been widely supplemented in feeds at sub-therapeutic concentrations to prevent post-weaning diarrhea and increase the overall productivity of pigs. However, the emergence of antimicrobial-resistant bacteria ... -
Dietary supplementation of red-osier dogwood polyphenol extract changes the ileal microbiota structure and increases Lactobacillus in a pig model
Zheng, Shugui; Song, Jichen; Qin, Xia; Yang, Kai; Liu, Mei; Yang, Chengbo; Nyachoti, Charles M. (2021-10-29)Abstract Red-osier dogwood (ROD) extract contains a lot of polyphenols that have the potential for modulation of gut microbiota. However, little information is available about its prebiotic properties. This ... -
Distribution and localization of porcine calcium sensing receptor (pCaSR) in different tissues of weaned piglets
Zhao, Xiaoya; Schindell, Brayden; Li, Weiqi; Ni, Liju; Liu, Shangxi; Wijerathne, Charith; Gong, Joshua; Nyachoti, Martin; O, Karmin; Yang, Chengbo (2019-03-19)Taste receptors including calcium sensing receptor (CaSR) are expressed in various animal tissues, and CaSR plays important roles in nutrient sensing and the physiology, growth and development of animals. However, molecular ... -
Effects of a microencapsulated formula of organic acids and essential oils on nutrient absorption, immunity, gut barrier function, and abundance of enterotoxigenic Escherichia coli F4 (ETEC F4) in weaned piglets challenged with ETEC F4
Choi, Janghan; Wang, Lucy; Liu, Shangxi; Lu, Peng; Zhao, Xiaoya; Liu, Haoming; Lahaya, Ludovic; Santin, Elizabeth; Liu, Song; Nyachoti, Martin; Yang, Chengbo (2020-08)Abstract: The objective was to study the effects of microencapsulated organic acids (OA) and essential oils (EO) on growth performance, immune system, gut barrier function, nutrient digestion and absorption, and abundance ... -
Eugenol attenuates inflammatory response and enhances barrier function during lipopolysaccharide (LPS)-induced inflammation in the porcine intestinal epithelial (IPEC-J2) cells
Hui, Qianru; Ammeter, Emily; Liu, Shangxi; Yang, Runqiang; Lu, Peng; Lahaya, Ludovic; Yang, Chengbo (2020-08)Eugenol (4-allyl-2-methoxyphenol) is an essential oil component, possessing anti-microbial, anti-inflammatory and anti-oxidative properties, however the effect of eugenol on porcine gut inflammation has not yet been ... -
Innovative drugs, chemicals, and enzymes within the animal production chain
Hassan, Yousef I; Lahaye, Ludovic; Gong, Max M; Peng, Jian; Gong, Joshua; Liu, Song; Gay, Cyril G; Yang, Chengbo (2018-07-31)Abstract The alarming number of recently reported human illnesses with bacterial infections resistant to multiple antibacterial agents has become a serious concern in recent years. This phenomenon is a core ... -
Thymol improves barrier function and attenuates inflammatory responses in porcine intestinal epithelial cells during lipopolysaccharide (LPS)-induced inflammation
Omonijo, Faith; Liu, Shangxi; Hui, Qianru; Zhang, Hua; Lahaye, Ludovic; Bodin, Jean-Christophe; Nyachoti, Martin; Yang, Chengbo (2018-12-19)It is well known that essential oil thymol exhibits anti-bacterial activity. The protective effects of thymol on pig intestine during inflammation is yet to be investigated. In this study, an in vitro (LPS)-induced ...