Browsing by Subject "p53"
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Characterization of the fitness of adenoviral E1A exon 1 deletion mutants and the role of SUMOylation in DREF function
(2022-07-04)Early region 1A (E1A) protein is the first protein expressed during the progression of adenoviral infection. E1A proteins push terminally differentiated cells back into the cell cycle through both altered cellular gene ... -
Mammalian Reovirus Infection Changes the Expression of Bcl-xL Protein in H1299 Cell Line Independent of p53
(2010-09-22)Mammalian reovirus (MRV) is a prototype virus of Reoviridae family. MRV virions are composed of two concentric protein capsids that surround a genome of 10 segments of dsRNA. It has been shown that MRV can manipulate host ... -
p53 mediates autophagy and cell death by a mechanism contingent upon Bnip3
(Hypertension, 2013-06)Autophagy is a process by which cells re-cycle organelles and macromolecular proteins during cellular stress. Defects in the regulation of autophagy have been associated with various human pathologies including heart ... -
p53 mediates cell death in the heart
(2019)During cellular stress, cells try to survive and overcome the stress by an essential process called autophagy. This process involves degrading and recycling organelles and macromolecules. Different human diseases such as ...