The treatment effects of dietary oils on diet-induced obesity, lipidemia, and insulin resistance in skeletal muscle tissue of obese prone rats

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dc.contributor.authorDunthorne, Karin
dc.contributor.examiningcommitteeAukema, Harold (Human Nutritional Sciences) Mizuno, Tooru (Physiology)en_US
dc.contributor.supervisorTaylor, Carla (Human Nutritional Sciences) Zahradka, Peter (Human Nutritional Sciences)en_US
dc.date.accessioned2011-08-25T20:26:34Z
dc.date.available2011-08-25T20:26:34Z
dc.date.issued2011-08-25
dc.degree.disciplineHuman Nutritional Sciencesen_US
dc.degree.levelMaster of Science (M.Sc.)en_US
dc.description.abstractReducing consumption of fat is recommended for obese individuals; however, altering dietary fat, without reducing total fat, may modify obesity-associated consequences. The effects of dietary fat composition on obesity and insulin resistance in diet-induced obese rats were investigated. Rats were fed a high-fat lard-based diet for 12 weeks and then were randomized into one of six high-fat treatment groups (oils used: high-oleic canola, conventional canola, high-oleic/conventional canola mix, conventional canola/flax mix, safflower, or soybean) or kept on the lard diet for 8 weeks. Diets had varying effects on lipidemia and glycemia; however, insulin tolerance tests, oral glucose tolerance tests, and the skeletal muscle response to insulin were not different among groups. Muscle phospholipids showed expected differences in fatty acid (FA) composition, but polyunsaturated/saturated FA ratios were not different among groups. Overall, a consistent response to high-fat diets was observed which may be attributed to the robustness of polyunsaturated/saturated FA ratios of muscle phospholipids.en_US
dc.description.noteOctober 2011en_US
dc.identifier.urihttp://hdl.handle.net/1993/4777
dc.language.isoengen_US
dc.rightsopen accessen_US
dc.subjectObesityen_US
dc.subjectMetabolismen_US
dc.subjectNutritionen_US
dc.subjectDiabetesen_US
dc.subjectCanolaen_US
dc.subjectOilen_US
dc.titleThe treatment effects of dietary oils on diet-induced obesity, lipidemia, and insulin resistance in skeletal muscle tissue of obese prone ratsen_US
dc.typemaster thesisen_US
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