Does Respiratory Syncytial Virus (RSV) infection in the first two years of life contribute to the development of asthma among children in Manitoba?
| dc.contributor.author | Khan, Sazzadul Khan | |
| dc.contributor.examiningcommittee | Elliott, Lawrence (Community Health Sciences) Becker, Allan (Pediatrics & Child Health) | en |
| dc.contributor.supervisor | Kozyrskyj, Anita (Community Health Sciences) | en |
| dc.date.accessioned | 2011-04-11T19:42:11Z | |
| dc.date.available | 2011-04-11T19:42:11Z | |
| dc.date.issued | 2011-04-11T19:42:11Z | |
| dc.degree.discipline | Community Health Sciences | en_US |
| dc.degree.level | Doctor of Philosophy (Ph.D.) | en_US |
| dc.description.abstract | The study was conducted with a total of 13980 children of the 1995 birth cohort, who were living in Manitoba by the end of December, 2006. Higher frequency of RSV-associated LRTI before 2 years was associated with higher risks of asthma diagnosis at 7 and 11 years and also with risks of transient wheeze and early persistent asthma. Higher risk of asthma diagnosis was associated with more severe episode(s) of RSV-associated LRTI within the first 2 years of life. First clinically significant RSV-LRTI between 6 and 12 months was associated with the highest risks of asthma diagnosis at 7 and at 11 years. But first RSV-associated LRTI within the first 6 months of life was associated with the highest risk of asthma/transient wheezing before the age of 3 years and early persistent asthma and transient wheeze. These associations were diminishing with increasing age of the children of the study cohort. | en |
| dc.description.note | May 2011 | en |
| dc.format.extent | 632493 bytes | |
| dc.format.mimetype | application/pdf | |
| dc.identifier.uri | http://hdl.handle.net/1993/4515 | |
| dc.language.iso | eng | en_US |
| dc.rights | open access | en_US |
| dc.subject | RSV | en |
| dc.subject | childhood-asthma | en |
| dc.title | Does Respiratory Syncytial Virus (RSV) infection in the first two years of life contribute to the development of asthma among children in Manitoba? | en |
| dc.type | doctoral thesis | en_US |