Immunocompetence in young and old laying hens in response to dietary folic acid and Escherichia coli lipopolysaccharide challenge

dc.contributor.authorMunyaka, Peris Mumbi
dc.contributor.examiningcommitteeHouse, J.D (Animal Science and Human Nutrition) Nyachoti, C.M (Animal Science) O, Karmin (Animal Science and Physiology) Holley, Rick (Food Science)en_US
dc.contributor.supervisorRodriguez-Lecompte, J.C. (Animal Science)en_US
dc.date.accessioned2012-09-06T20:44:59Z
dc.date.available2012-09-06T20:44:59Z
dc.date.issued2012-09-06
dc.degree.disciplineAnimal Scienceen_US
dc.degree.levelMaster of Science (M.Sc.)en_US
dc.description.abstractWe investigated the effects of dietary folic acid and age, on immunological parameters in laying hens challenged with LPS. 48 Shaver White hens at different ages were fed 2 wheat-soybean based diets with 0 or 4 mg supplemental FA per kg of diet for 8 wk. 6 hens from each dietary treatment were injected with 8 mg/kg body weight of LPS or saline and observed for 4 h. A few diet X challenge interaction were observed in young hens, whereas FA and LPS independently influenced a number of parameters. In older hens, there were very few diet X challenge interactions as well as effects of FA, whereas LPS affected several parameters. In conclusion, dietary FA influenced some immune responses in younger hens, but no such effects were observed in older hens. FA may modulate immune responses in laying hens under acute LPS challenge which could be tissue and age dependent.en_US
dc.description.noteOctober 2012en_US
dc.identifier.urihttp://hdl.handle.net/1993/8612
dc.language.isoengen_US
dc.rightsopen accessen_US
dc.subjectfolic aciden_US
dc.subjectlipopolysaccharideen_US
dc.subjectimmune responseen_US
dc.subjectlaying henen_US
dc.subjectageen_US
dc.titleImmunocompetence in young and old laying hens in response to dietary folic acid and Escherichia coli lipopolysaccharide challengeen_US
dc.typemaster thesisen_US
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