The effects of dietary zinc on adipocyte Glut 4 expression, adiposity, hyperinsulinemia and zinc status of the obese, fa/fa, Zucker rat
| dc.contributor.author | Petroulakis, Kathy | en_US |
| dc.date.accessioned | 2007-07-12T17:49:58Z | |
| dc.date.available | 2007-07-12T17:49:58Z | |
| dc.date.issued | 2000-05-01T00:00:00Z | en_US |
| dc.degree.discipline | Foods and Nutrition | en_US |
| dc.degree.level | Master of Science (M.Sc.) | en_US |
| dc.description.abstract | The primary objective of this study was to investigate the effects of dietary zinc manipulation on the expression of total Glut 4 in adipocytes of lean and obese (fa/fa) Zucker rats. The study was further designed to investigate the effects of dietary zinc deficiency and supplementation on (1) body fat deposition (adiposity), (2) hyperinsulinemia and (3) zinc status of the Zucker rat. Weanling lean and fa/fa Zucker rats were fed zinc-deficient (ZD, 5 ppm zinc), zinc control (ZC, 30 ppm zinc), or zinc-supplemented (ZS, 150 ppm zinc) diets, or were pair-weighed (PW, 30 ppm zinc) for 9 weeks. At 15 weeks of age, rats were assessed for total Glut 4 expression in adipocytes, fat deposition (epididymal and perirenal fat pad weights; epididymal adipocyte diameter; liver lipid concentration), degree of insulin resistance (serum insulin and glucose concentrations) and tissue zinc concentrations (femur, serum and liver). (Abstract shortened by UMI.) | en_US |
| dc.format.extent | 6803249 bytes | |
| dc.format.extent | 184 bytes | |
| dc.format.mimetype | application/pdf | |
| dc.format.mimetype | text/plain | |
| dc.identifier.uri | http://hdl.handle.net/1993/2586 | |
| dc.language.iso | eng | en_US |
| dc.rights | open access | en_US |
| dc.title | The effects of dietary zinc on adipocyte Glut 4 expression, adiposity, hyperinsulinemia and zinc status of the obese, fa/fa, Zucker rat | en_US |
| dc.type | master thesis | en_US |