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dc.contributor.supervisor Morrison, Jason (Biosystems Engineering) en_US
dc.contributor.author Gascoyne, Trevor
dc.date.accessioned 2012-09-21T22:10:28Z
dc.date.available 2012-09-21T22:10:28Z
dc.date.issued 2012-09-21
dc.identifier.uri http://hdl.handle.net/1993/8914
dc.description.abstract There is a need for a repeatable method of measuring polyethylene wear in total knee re-placement (TKA). Model-based radiostereometric analysis (MBRSA) is a high accuracy diagnostic tool with the potential to meet this need; however, a number of unknowns must be examined. This research examines optimized patient positioning for MBRSA imaging as well as in vitro validation of a wear measurement technique using a loaded TKA phantom to mimic patient physiology. Imaging along the antero-posterior and medio-lateral axes of the patient achieved op-timal MBRSA accuracy of better than 0.035 mm (in-plane) and 0.12° (in-plane). The de-veloped MBRSA technique underestimated TKA wear on previously-worn polyethylene bearings; however, a number of factors can be corrected to improve this discrepancy. This research provides an overall methodology for measuring TKA wear, but additional experimentation and an improved physiological phantom are needed to obtain accurate wear measurement. en_US
dc.rights info:eu-repo/semantics/openAccess
dc.subject Arthroplasty en_US
dc.subject Radiology en_US
dc.title Evaluation of model-based RSA for in vivo measurement of polyethylene wear in a total knee replacement en_US
dc.type info:eu-repo/semantics/masterThesis
dc.degree.discipline Biosystems Engineering en_US
dc.contributor.examiningcommittee Paliwal, Jitendra (Biosystems Engineering) Turgeon, Thomas (Surgery) en_US
dc.degree.level Master of Science (M.Sc.) en_US
dc.description.note October 2012 en_US


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