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'The influence of gestational age and socioeconomic status on neonatal outcomes in late preterm and early term gestation: a population based study'

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dc.contributor.author Ruth, Chelsea A
dc.contributor.author Roos, Noralou
dc.contributor.author Hildes-Ripstein, Elske
dc.contributor.author Brownell, Marni
dc.date.accessioned 2012-08-03T11:41:43Z
dc.date.available 2012-08-03T11:41:43Z
dc.date.issued 2012-06-29
dc.identifier.citation BMC Pregnancy and Childbirth. 2012 Jun 29;12(1):62
dc.identifier.uri http://hdl.handle.net/1993/8138
dc.description.abstract AbstractBackgroundInfants born late preterm (34 + 0 to 36 + 6 weeks GA (gestational age)) are known to have higher neonatal morbidity than term (37 + 0 to 41 + 6 weeks GA) infants. There is emerging evidence that these risks may not be homogenous within the term cohort and may be higher in early term (37 + 0 to 38 + 6 weeks GA). These risks may also be affected by socioeconomic status, a risk factor for preterm birth.MethodsA retrospective population based cohort of infants born at 34 to 41 weeks of GA was assembled; individual and area-level income was used to develop three socioeconomic (SES) groups. Neonatal morbidity was grouped into respiratory distress syndrome (RDS), other respiratory disorders, other complications of prematurity, admission to a Level II/III nursery and receipt of phototherapy. Regression models were constructed to examine the relationship of GA and SES to neonatal morbidity while controlling for other perinatal variables.ResultsThe cohort contained 25 312 infants of whom 6.1% (n = 1524) were born preterm and 32.4% (n = 8203) were of low SES. Using 39/40 weeks GA as the reference group there was a decrease in neonatal morbidity at each week of gestation. The odds ratios remained significantly higher at 37 weeks for RDS or other respiratory disorders, and at 38 weeks for all other outcomes. SES had an independent effect, increasing morbidity with odds ratios ranging from 1.2–1.5 for all outcomes except for the RDS group, where it was not significant.ConclusionsThe risks of morbidity fell throughout late preterm and early term gestation for both respiratory and non-respiratory morbidity. Low SES was associated with an independent increased risk. Recognition that the morbidities associated with prematurity continue into early term gestation and are further compounded by SES is important to develop strategies for improving care of early term infants, avoiding iatrogenic complications and prioritizing public health interventions.
dc.title 'The influence of gestational age and socioeconomic status on neonatal outcomes in late preterm and early term gestation: a population based study'
dc.type Journal Article
dc.language.rfc3066 en
dc.description.version Peer Reviewed
dc.rights.holder Chelsea A Ruth et al.; licensee BioMed Central Ltd.
dc.date.updated 2012-08-03T11:41:43Z
dc.identifier.doi http://dx.doi.org/10.1186/1471-2393-12-62


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