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Identifying the functional relevance of CD271 and CD133 in medulloblastoma tumor formation
(2012-11-22)
Medulloblastoma (MB) is the most common primary malignant pediatric brain
tumor. The relationship between stem cell function and invasiveness has not been
investigated in MB. We have dissected MB heterogeneity and compared ...
VDAC and BNIP3: a crucial interaction's role in delayed neuronal cell death in stroke
(2012-11-23)
Stroke is currently the third-leading cause of death, and the primary cause of disability in Canada. In a stroke, the majority of neuron death is due to apoptosis triggered by stress from the ischemic insult. In theory, ...
Predicting risk of mortality in dialysis patients: prognostic value of a simple chest x-ray
(2012-11-22)
Patients with kidney failure on dialysis are at high risk for cardiovascular disease and premature death in aggregate. Individual patient risk, however, varies widely. Improved ascertainment of individual risk could inform ...
Using diffusion MRI technique as a tool in the early detection of Alzheimer's Disease
(2012-11-23)
Alzheimer's Disease (AD) is a neurodegenerative disorder that currently affects an estimated 500 000 Canadians, a prevalence that is expected to double within the next 25 years. It is projected that AD will impact the lives ...
Booster seat promotion in Winnipeg: Evaluation of a campaign targeting parents
(2012-11-23)
Motor vehicle collisions are the leading cause of injury death for Canadian
children, with improper restraint being an important and preventable contributing factor.
Children 4-8 years of age are the least likely to be ...
Quality of life, depression and anxiety in women with abnormal uterine bleeding.
(2012-11-23)
Abnormal uterine bleeding (AUB) defines any change in the duration , frequency or flow
volume of periods or bleeding between periods. Women experiencing these symptoms are known to have reduced quality of life and experience ...
Does perioperative nutrition improve clinical outcomes in patients undergoing upper gastrointestinal surgery?: A network meta-analysis.
(2012-11-23)
Each year in Canada, more than 2000 patients undergo surgical resection for treatment of
esophageal, pancreatic or stomach cancer. However, resection of upper gastrointestinal
(GI) malignancies is associated with significant ...
MicroRNA-301a attenuates collagen gel contractility and promotes proliferation of human bone marrow derived mesenchymal stem cells
(2012-11-23)
Previous data in our lab suggests that human mesenchymal stem cells (MSCs) of bone marrow
origin display a myofibroblast phenotype in vitro. Coincident with the onset of a myofibroblast phenotype, we observed a reduction ...
Operation inspiration: patients, puffers and plans for action - effect of web-based asthma management on asthma patient care and satisfaction
(2012-11-23)
Asthma is a common health problem in Canada and around the world. When asthma is not well controlled, it leads to increased use of SABAs (e.g. salbutamol), an increased number of physician and emergency room visits and a ...
Assessing digital tomosynthesis for paediatric sacroiliac joint imaging
(2012-11-23)
Objective: To assess the use of digital tomosynthesis (DT) as an alternative imaging modality to radiography for the imaging of paediatric sacroiliac (SI) joints.
Methods: Three anthropomorphic pelvis phantoms were imaged ...