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Is flaxseed equivalent and/or synergistic with ACE inhibition in the prevention of chemotherapy-mediated cardiotoxicity?
(2021-08)
Background: Two commonly used anti-cancer agents for patients with breast cancer are Doxorubicin (DOX) and Trastuzumab (TRZ). Despite their efficacy in reducing the morbidity and mortality of individuals with breast cancer, ...
Investigation of the Disease Manifestations and Genetics of a novel TDP1 Mutation, the gene implicated in Spinocerebellar Ataxia with Axonal Neuropathy 1 (SCAN1)
(2020-08-06)
Tyrosyl-DNA phosphodiesterase 1 (TDP1) is a protein best-characterized in its DNA repair role via resolution of stalled Topoisomerase1-DNA (TOP1-DNA) complexes. These stalled complexes would otherwise collide with DNA ...
Pre-Surgical Mental Health Readiness Assessments for Gender Affirming Surgeries: A Survey of Canadian Practices
(2020-07-31)
Practitioners providing pre-surgical assessments for gender affirming surgery in Canada (N=70) were surveyed on their assessment procedures, their interpretations of the World Professional Association for Transgender Health ...
Frontotemporal Dementia-related glucose metabolic pattern assessed by FDG-PET
(2020-08-06)
Alzheimer's disease (AD) and Frontotemporal Dementia (FTD) are leading causes of dementia.