Chronic kidney disease (CKD) is a major public health problem with an increasing incidence and prevalence worldwide. Patients with CKD, and particularly those with kidney failure on dialysis, have exceedingly high rates ...

Melanoma arises from melanocytes in the skin (cutaneous) or mucosa (mucosal). It is one of the most aggressive skin cancers when compared to other, non-melanoma skin cancers. Worldwide, melanoma represents 4% of all skin ...

Pleural empyema is a purulent pleural effusion. It is a known, albeit infrequent, complication of pneumonia. To treat a pleural empyema, antibiotics and sufficient drainage are required. Surgical intervention is often ...

Osteoporosis is a major risk factor for debilitating fractures in geriatric populations. It is increasingly recognized that osteoporosis originates in early life, long before symptoms manifest in late adulthood. Breastfeeding ...

Lower limb complications (foot ulcers and lower limb amputations) are major problems commonly seen in patients with peripheral vascular disease (PVD) and chronic kidney disease (CKD). Lower limb complications are a significant ...

In spite of the benefits of antiretroviral therapy (ART), immune activation remains higher in HIV-positive individuals on ART than in non-infected persons.1 2 Furthermore, chronic inflammation in HIV-positive persons on ...

Prior analyses by the Manitoba Ovarian Cancer Outcomes study group identified that late-stage ovarian cancer patients receiving neoadjuvant chemotherapy had poorer survival than patients receiving adjuvant chemotherapy. ...

In North America, the incidence of thyroid cancer is increasing by over 6% every year. A population based cohort of 2306 consecutive thyroid cancers (170-2010) has already been established and followed in the province of ...