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dc.contributor.supervisor Moghadasian, Mohammed (Human Nutritional Sciences) en
dc.contributor.author Azordegan, Nazila
dc.date.accessioned 2010-09-21T20:36:15Z
dc.date.available 2010-09-21T20:36:15Z
dc.date.issued 2010-09-21T20:36:15Z
dc.identifier.uri http://hdl.handle.net/1993/4215
dc.description.abstract This study was carried out to investigate the fatty acid composition of tumoral, marginal and normal breast tissue in female breast cancer patients. Patients were recruited from St. Boniface General Hospital. A pre-operative blood sample was drawn. After surgery, sections were obtained from tumoral, marginal and normal breast tissues for histology and biochemical analysis. Extracted lipids from marginal tissue were significantly higher than those in normal or tumoral tissue. The lipid profile in tumoral tissue was significantly different in terms of fatty acid composition compared to normal and marginal tissue with less linoleic and alpha linolenic acid and more long chain polyunsaturated fatty acid of omega-3 and omega-6 series. Marginal tissue showed significantly less alpha linolenic acid compared to normal tissue. An inverse correlation existed between plasma level of 22:6 n-3 and breast cancer stage. We found different lipid profile in tumoral tissue compared to normal and marginal tissue. en
dc.format.extent 1135974 bytes
dc.format.mimetype application/pdf
dc.language.iso en_US
dc.rights info:eu-repo/semantics/openAccess
dc.subject Breast cancer en
dc.subject fatty acids en
dc.subject lipid en
dc.subject tumor en
dc.title Characterization of fatty acid profile in breast tissues from Manitoba breast cancer patients en
dc.type info:eu-repo/semantics/masterThesis
dc.degree.discipline Human Nutritional Sciences en
dc.contributor.examiningcommittee Eskin, Michael (Human Nutritional Sciences) Fraser, Virginia (Surgery) Fischer, Gabor (Pathology) en
dc.degree.level Master of Science (M.Sc.) en
dc.description.note October 2010 en


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