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dc.contributor.supervisorMoghadasian, Mohammed (Human Nutritional Sciences)en
dc.contributor.authorAzordegan, Nazila
dc.date.accessioned2010-09-21T20:36:15Z
dc.date.available2010-09-21T20:36:15Z
dc.date.issued2010-09-21T20:36:15Z
dc.identifier.urihttp://hdl.handle.net/1993/4215
dc.description.abstractThis study was carried out to investigate the fatty acid composition of tumoral, marginal and normal breast tissue in female breast cancer patients. Patients were recruited from St. Boniface General Hospital. A pre-operative blood sample was drawn. After surgery, sections were obtained from tumoral, marginal and normal breast tissues for histology and biochemical analysis. Extracted lipids from marginal tissue were significantly higher than those in normal or tumoral tissue. The lipid profile in tumoral tissue was significantly different in terms of fatty acid composition compared to normal and marginal tissue with less linoleic and alpha linolenic acid and more long chain polyunsaturated fatty acid of omega-3 and omega-6 series. Marginal tissue showed significantly less alpha linolenic acid compared to normal tissue. An inverse correlation existed between plasma level of 22:6 n-3 and breast cancer stage. We found different lipid profile in tumoral tissue compared to normal and marginal tissue.en
dc.format.extent1135974 bytes
dc.format.mimetypeapplication/pdf
dc.language.isoengen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBreast canceren
dc.subjectfatty acidsen
dc.subjectlipiden
dc.subjecttumoren
dc.titleCharacterization of fatty acid profile in breast tissues from Manitoba breast cancer patientsen
dc.typeinfo:eu-repo/semantics/masterThesis
dc.typemaster thesisen_US
dc.degree.disciplineHuman Nutritional Sciencesen_US
dc.contributor.examiningcommitteeEskin, Michael (Human Nutritional Sciences) Fraser, Virginia (Surgery) Fischer, Gabor (Pathology)en
dc.degree.levelMaster of Science (M.Sc.)en_US
dc.description.noteOctober 2010en


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