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dc.contributor.supervisor Ivanco, Tammy (Psychology) en
dc.contributor.author Hartle, Kelly D.
dc.date.accessioned 2010-09-10T12:01:40Z
dc.date.available 2010-09-10T12:01:40Z
dc.date.issued 2010-09-10T12:01:40Z
dc.identifier.uri http://hdl.handle.net/1993/4119
dc.description.abstract The brain responds to injury during early development with alterations in behaviour and dendritic morphology of motor cortex neurons. Rats were exposed to damage either prenatally or after the first postnatal week, using different models of damage and motor cortex was examined. Prenatal injury resulted in a decrease in length, complexity and volume in layer II neurons, but no differences in layer V neurons or behavioural tasks. Postnatal damage produced increases in length of basilar dendrites, but no differences in spine density at 2 months of age, whereas at 6 months of age, an overall decrease in apical and basilar spine density was observed. Findings demonstrate the maturational status of the brain at the time of injury play a crucial role in response to injury. en
dc.format.extent 2201934 bytes
dc.format.mimetype application/pdf
dc.language.iso en_US
dc.rights info:eu-repo/semantics/openAccess
dc.subject Development en
dc.subject Golgi en
dc.subject Injury en
dc.subject Pyramidal Neurons en
dc.title The neuroanatomical effect of brain injury during early development in a rat model en
dc.type info:eu-repo/semantics/doctoralThesis
dc.degree.discipline Psychology en
dc.contributor.examiningcommittee Marotta, Jonathan (Psychology) Larson, Susan (Psychology) Del Bigio, Marc (Pathology) Saucier, Deborah (University of Lethbridge) en
dc.degree.level Doctor of Philosophy (Ph.D.) en
dc.description.note October 2010 en


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