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The utilization of pharmaceutical cannabinoid agents in Manitoba, Canada. A population-based study using administrative health care data.

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dc.contributor.supervisor Leong, Christine (Pharmacy) en_US
dc.contributor.author Alkabbani, Wajd
dc.date.accessioned 2019-03-01T17:19:12Z
dc.date.available 2019-03-01T17:19:12Z
dc.date.issued 2019-02 en_US
dc.date.submitted 2019-03-01T16:36:04Z en
dc.identifier.citation Alkabbani W, Marrie RA, Bugden S, Alessi-Severini S, Daeninck P, Bolton JM, Sareen J, Leong, C. Pharmaceutical cannabinoid use in Manitoba, 2004/05 to 2014/15: a population-based cross-sectional study. CMAJ Open. 2018;6(4):E637-E642. en_US
dc.identifier.uri http://hdl.handle.net/1993/33777
dc.description.abstract Introduction: Pharmaceutical cannabinoids are third-line therapeutic options for several indications, despite the lack of strong evidence to support their efficacy. The extent and patterns of their utilization from a population perspective are unknown. Methods: A retrospective population-based study using administrative healthcare data from Apr.1, 2004 to Mar.31, 2017, to assess the annual trends, demographic and clinical determinants, and persistence of pharmaceutical cannabinoids use. Results: The incident and prevalent users of cannabinoid agents increased throughout the study period. Nabilone comprised the majority of dispensations. The percent of users who had a diagnosis for the approved indications was relatively low. Persistence of cannabinoid use was low and influenced by the socio-demographics and medical conditions of users. Conclusion: Although the rates of pharmaceutical cannabinoid use have increased, the overall low numbers of users and the high discontinuation rates reflect the lack of effectiveness and tolerability to these agents. en_US
dc.subject Drug utilization en_US
dc.subject Cannabinoids en_US
dc.subject pharmacoepidemiology en_US
dc.subject Administrative data en_US
dc.title The utilization of pharmaceutical cannabinoid agents in Manitoba, Canada. A population-based study using administrative health care data. en_US
dc.degree.discipline Pharmacy en_US
dc.contributor.examiningcommittee Bugden, Shawn (Pharmacy) Alessi-Severini, Silvia (Pharmacy) Marrie, Ruth Ann (Internal Medicine) en_US
dc.degree.level Master of Science (M.Sc.) en_US
dc.description.note May 2019 en_US


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