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dc.contributor.supervisor Song Liu (Biosystem Engineering) en_US
dc.contributor.author Sedigheh, Nazaripour
dc.date.accessioned 2016-09-20T17:10:50Z
dc.date.available 2016-09-20T17:10:50Z
dc.date.issued 2016
dc.identifier.uri http://hdl.handle.net/1993/31828
dc.description.abstract A new pH sensitive polyurethane intravaginal ring reservoir (PU Res IVR) drug delivery system was developed using a novel and versatile method. A combination of surface-initiated activator regenerated by electron transfer atom transfer radical polymerization (SI-ARGET-ATRP) and alkyne-azide click reaction was applied to graft pH sensitive polymers with different functional groups from the surface of PU Res IVR segments. Release studies showed that the dominant mechanism is " the through pore mechanism" in this system. en_US
dc.subject pH Responsive, Polymer Brushes, Intravagianl Ring, Stimuli-Responsive, en_US
dc.title pH Responsive Polymer Brushes grafted from the surface of Intravaginal Ring for on-demand drug delivery en_US
dc.degree.discipline Chemistry en_US
dc.contributor.examiningcommittee Joe O'Neil (Chemistry) Emmanuel A. Ho (Pharmacy) en_US
dc.degree.level Master of Science (M.Sc.) en_US
dc.description.note October 2016 en_US


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