Home

Current views concerning the influences of murine hepatic endothelial adhesive and cytotoxic properties on interactions between metastatic tumor cells and the liver

Show simple item record

dc.contributor.author Wang, Hui H
dc.contributor.author Qiu, Hongming
dc.contributor.author Qi, Ke
dc.contributor.author Orr, F W
dc.date.accessioned 2016-01-22T20:14:29Z
dc.date.available 2016-01-22T20:14:29Z
dc.date.issued 2005-12-09
dc.identifier.citation Comparative Hepatology. 2005 Dec 09;4(1):8
dc.identifier.uri http://dx.doi.org/10.1186/1476-5926-4-8
dc.identifier.uri http://hdl.handle.net/1993/31110
dc.description.abstract Abstract Substantial recent experimental evidence has demonstrated the existence of reciprocal interactions between the microvascular bed of a specific organ and intravascular metastatic tumor cells through expression of adhesion molecules and nitric oxide release, resulting in a significant impact upon metastatic outcomes. This review summarizes the current findings of adhesive and cytotoxic endothelial-tumor cell interactions in the liver, the inducibility, zonal distribution and sinusoidal structural influences on the hepatic endothelial regulatory functions, and the effects of these functions on the formation of liver cancer metastases. New insights into the traditional cancer metastatic cascade are also discussed.
dc.title Current views concerning the influences of murine hepatic endothelial adhesive and cytotoxic properties on interactions between metastatic tumor cells and the liver
dc.type Journal Article
dc.language.rfc3066 en
dc.rights.holder Wang et al; licensee BioMed Central Ltd.
dc.date.updated 2016-01-22T07:03:08Z


Files in this item

This item appears in the following Collection(s)

  • Research Publications [1146]
    This collection contains full text research publications authored or co-authored by University of Manitoba researchers.

Show simple item record

View Statistics