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Now showing items 21-30 of 143
Differential item functioning of the SF-12 in a population-based regional joint replacement registry
(2019-07-02)
Abstract
Background
Joint replacement, an increasingly common procedure amongst older adults, can substantially improve health-related quality of life (HRQoL). However, ...
Qualitative insights into adapting an in-lab empathy intervention for use via videoconferencing with groups of nursing students
(2019)
Caregivers often feel neglected by health care providers who lack communication skills or make assumptions about them. Therefore it is important for health care providers to receive communication training and education ...
Noncovalent SUMO-interaction motifs in HIV integrase play important roles in SUMOylation, cofactor binding, and virus replication
(2019-04-02)
Abstract
Background
HIV integrase (IN) and its cellular cofactors, including lens-epithelium-derived growth factor (LEDGF/p75), Ku70, p300, and Rad52, are subject to small ...
Diagnostic delay is common among patients with hypophosphatasia: initial findings from a longitudinal, prospective, global registry
(2019-02-14)
Abstract
Background
Hypophosphatasia (HPP) is a rare, systemic disease caused by mutation(s) within the ALPL gene encoding tissue-nonspecific alkaline phosphatase (ALP). HPP ...
Underutilized and undertheorized: the use of hospitalization for ambulatory care sensitive conditions for assessing the extent to which primary healthcare services are meeting needs in British Columbia First Nation communities
(2019-01-18)
Abstract
Background
Since the 1960s, the federal government has been providing or funding a selection of community-based primary healthcare (PHC) programs on First Nations ...
Copy number variation-based gene set analysis reveals cytokine signalling pathways associated with psychiatric comorbidity in patients with inflammatory bowel disease
(2019-05)
Background
Recent studies discovered many genetic variants associated with both psychiatric and inflammatory disorders, but the role of genetic factors in the development of psychiatric comorbidity (PC) in inflammatory ...
Comparative effectiveness of the different components of care provided in heart failure clinics—protocol for a systematic review and network meta-analysis
(2019-02-02)
Abstract
Background
Heart failure (HF) is a complex chronic condition, leading to frequent hospitalization, decreased quality of life, and increased mortality. Current guidelines ...
Estimating random walk centrality in networks
(Computational Statistics & Data Analysis 138, pp. 190-200., 2019)
Random walk centrality (equivalently, the accessibility index) for the states of a time-homogeneous irreducible Markov chain on a finite state space is considered. It is known that the accessibility index for a particular ...
Inappropriateness of health care in Canada: a systematic review protocol
(2019-02-11)
Abstract
Background
There is increasing recognition in Canada and globally that a substantial proportion of health care delivered is inappropriate as evidenced by (1) harmful ...
Health-related quality of life worsens by school age amongst children with food allergy
(2019-02-07)
Abstract
Background
Food allergy is negatively associated with health-related quality of life (HRQL). Although differences exist between parents and children, less is known ...