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The effects of dietary zinc on adipocyte Glut 4 expression, adiposity, hyperinsulinemia and zinc status of the obese, fa/fa, Zucker rat

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dc.contributor.author Petroulakis, Kathy en_US
dc.date.accessioned 2007-07-12T17:49:58Z
dc.date.available 2007-07-12T17:49:58Z
dc.date.issued 2000-05-01T00:00:00Z en_US
dc.identifier.uri http://hdl.handle.net/1993/2586
dc.description.abstract The primary objective of this study was to investigate the effects of dietary zinc manipulation on the expression of total Glut 4 in adipocytes of lean and obese (fa/fa) Zucker rats. The study was further designed to investigate the effects of dietary zinc deficiency and supplementation on (1) body fat deposition (adiposity), (2) hyperinsulinemia and (3) zinc status of the Zucker rat. Weanling lean and fa/fa Zucker rats were fed zinc-deficient (ZD, 5 ppm zinc), zinc control (ZC, 30 ppm zinc), or zinc-supplemented (ZS, 150 ppm zinc) diets, or were pair-weighed (PW, 30 ppm zinc) for 9 weeks. At 15 weeks of age, rats were assessed for total Glut 4 expression in adipocytes, fat deposition (epididymal and perirenal fat pad weights; epididymal adipocyte diameter; liver lipid concentration), degree of insulin resistance (serum insulin and glucose concentrations) and tissue zinc concentrations (femur, serum and liver). (Abstract shortened by UMI.) en_US
dc.format.extent 6803249 bytes
dc.format.extent 184 bytes
dc.format.mimetype application/pdf
dc.format.mimetype text/plain
dc.language en en_US
dc.language.iso en_US
dc.rights info:eu-repo/semantics/openAccess
dc.title The effects of dietary zinc on adipocyte Glut 4 expression, adiposity, hyperinsulinemia and zinc status of the obese, fa/fa, Zucker rat en_US
dc.type info:eu-repo/semantics/masterThesis
dc.type master thesis en_US
dc.degree.discipline Foods and Nutrition en_US
dc.degree.level Master of Science (M.Sc.) en_US


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