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dc.contributor.author Nicolle, Lindsay E
dc.date.accessioned 2014-02-21T20:06:10Z
dc.date.available 2014-02-21T20:06:10Z
dc.date.issued 2014-02-12
dc.identifier.citation Antimicrobial Resistance and Infection Control. 2014 Feb 12;3(1):6
dc.identifier.uri http://hdl.handle.net/1993/23315
dc.description.abstract Abstract Intense antimicrobial use in long term care facilities promotes the emergence and persistence of antimicrobial resistant organisms and leads to adverse effects such as C. difficile colitis. Guidelines recommend development of antimicrobial stewardship programs for these facilities to promote optimal antimicrobial use. However, the effectiveness of these programs or the contribution of any specific program component is not known. For this review, publications describing evaluation of antimicrobial stewardship programs for long term care facilities were identified through a systematic literature search. Interventions included education, guidelines development, feedback to practitioners, and infectious disease consultation. The studies reviewed varied in types of facilities, interventions used, implementation, and evaluation. Comprehensive programs addressing all infections were reported to have improved antimicrobial use for at least some outcomes. Targeted programs for treatment of pneumonia were minimally effective, and only for indicators of uncertain relevance for stewardship. Programs focusing on specific aspects of treatment of urinary infection – limiting treatment of asymptomatic bacteriuria or prophylaxis of urinary infection – were reported to be effective. There were no reports of cost-effectiveness, and the sustainability of most of the programs is unclear. There is a need for further evaluation to characterize effective antimicrobial stewardship for long term care facilities.
dc.rights info:eu-repo/semantics/openAccess
dc.title Antimicrobial stewardship in long term care facilities: what is effective?
dc.type Journal Article
dc.type info:eu-repo/semantics/article
dc.language.rfc3066 en
dc.description.version Peer Reviewed
dc.rights.holder Lindsay E Nicolle et al.; licensee BioMed Central Ltd.
dc.date.updated 2014-02-21T20:06:11Z
dc.identifier.doi http://dx.doi.org/10.1186/2047-2994-3-6


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