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dc.contributor.author Bernstein, Matthew T
dc.contributor.author Graff, Lesley A
dc.contributor.author Avery, Lisa
dc.contributor.author Palatnick, Carrie
dc.contributor.author Parnerowski, Katie
dc.contributor.author Targownik, Laura E
dc.date.accessioned 2014-01-25T08:30:01Z
dc.date.available 2014-01-25T08:30:01Z
dc.date.issued 2014-01-22
dc.identifier.citation BMC Women's Health. 2014 Jan 22;14(1):14
dc.identifier.uri http://hdl.handle.net/1993/23278
dc.description.abstract Abstract Background Little is known as to the extent gastrointestinal (GI) complaints are reported by women around menses. We aimed to describe GI symptoms that occurred premenstrually and during menses in healthy women, and to specifically assess the relationship of emotional symptoms to GI symptoms around menses. Methods We recruited healthy, premenopausal adult women with no indication of GI, gynecologic, or psychiatric disease who were attending an outpatient gynecology clinic for well-woman care. They completed a survey that queried menstrual histories and the presence of GI and emotional symptoms. We compared the prevalence of primary GI symptoms (abdominal pain, diarrhea, constipation, nausea, vomiting), as well as pelvic pain and bloating, in the 5 days preceding menses and during menses, and assessed whether emotional symptoms or other factors were associated with the occurrence of GI symptoms. Results Of 156 respondents, 73% experienced at least one of the primary GI symptoms either pre- or during menses, with abdominal pain (58% pre; 55% during) and diarrhea (24% pre; 28% during) being the most common. Those experiencing any emotional symptoms versus those without were more likely to report multiple (2 or more) primary GI symptoms, both premenstrually (depressed p = 0.006; anxiety p = 0.014) and during menses (depressed p < 0.001; anxiety p = 0.008). Fatigue was also very common (53% pre; 49% during), and was significantly associated with multiple GI symptoms in both menstrual cycle phases (pre p < 0.001; during p = 0.01). Conclusions Emotional symptoms occurring in conjunction with GI symptoms are common perimenstrually, and as such may reflect shared underlying processes that intersect brain, gut, and hormonal pathways.
dc.title Gastrointestinal symptoms before and during menses in healthy women
dc.type Journal Article
dc.language.rfc3066 en
dc.description.version Peer Reviewed
dc.rights.holder Matthew T Bernstein et al.; licensee BioMed Central Ltd.
dc.date.updated 2014-01-25T08:30:02Z
dc.identifier.doi http://dx.doi.org/10.1186/1472-6874-14-14


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