• Libraries
    • Log in to:
    View Item 
    •   MSpace Home
    • Faculty of Graduate Studies (Electronic Theses and Practica)
    • FGS - Electronic Theses and Practica
    • View Item
    •   MSpace Home
    • Faculty of Graduate Studies (Electronic Theses and Practica)
    • FGS - Electronic Theses and Practica
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Tonic and phasic depression of Ia EPSPs during fictive locomotion

    Thumbnail
    View/Open
    MQ41707.pdf (3.598Mb)
    Date
    1999-04-01
    Author
    Gosgnach, Simon
    Metadata
    Show full item record
    Abstract
    Intracellular recordings from hindlimb $\alpha$-motoneurons were used to examine the effects of fictive locomotion, evoked by stimulation of the midbrain locomotor region (MLR), on group Ia monosynaptic excitatory postsynaptic potentials (EPSPs). The EPSPs were evoked from homonymous or close synergist afferents by electrical stimulation of peripheral nerves at group I strength ($\le$2T). The intracellular recordings were used to examine differences in EPSP amplitude between the locomotor and non-locomotor state as well as the modulation of EPSP amplitude between the flexor and extensor phases of locomotion. The present study is the first to investigate the change of composite group Ia monosynaptic EPSP amplitude between the locomotor and non-locomotor states. In order to investigate group I synaptic activity in the vicinity of the $\alpha$-motoneurons, extracellular field potential (EFP) amplitudes recorded in the ventral horn were examined before, during and after locomotion. Taken toge her, the decrease in monosynaptic EPSP amplitude, the poor correlation between motoneuron membrane resistance and EPSP decreases, and the decreases in group I EFPs during locomotion are consistent with the hypothesis that during fictive locomotion there is a specific regulation of synaptic transmission from group Ia afferents to motoneurons. (Abstract shortened by UMI.)
    URI
    http://hdl.handle.net/1993/1993
    Collections
    • FGS - Electronic Theses and Practica [25494]

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV
     

     

    Browse

    All of MSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    Login

    Statistics

    View Usage Statistics

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV