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dc.contributor.supervisor Hultin, Philip G. (Chemistry) en_US
dc.contributor.author McFarlane, Michael Thomas
dc.date.accessioned 2012-12-19T18:00:32Z
dc.date.available 2012-12-19T18:00:32Z
dc.date.issued 2012-12-19
dc.identifier.uri http://hdl.handle.net/1993/13706
dc.description.abstract Creating new carbon-carbon bonds is one of the most important and challenging reactions in organic synthesis. Metal-catalyzed cross-coupling reactions have emerged as one of the preferred methods of producing new carbon-carbon bonds, and this work led to the 2010 Nobel Prize in Chemistry. This thesis was aimed at expanding the current research in the area of metal-catalyzed cross-coupling reactions to include new applications with dithiolane and dithiane protecting groups. 1,3-Dithiolane and 1,3-dithiane derivatives are particularly interesting molecules in that they can be deprotonated by a strong base to form anions, which can then be used for carbon-carbon bond synthesis. This thesis describes the investigation into the use of dithiolanes and dithianes in metal-catalyzed cross-coupling reactions, as well as some of the challenges faced in performing this sulfur-based chemistry. en_US
dc.subject cross-coupling en_US
dc.subject thioacetal en_US
dc.subject organohalide en_US
dc.subject Umpolung en_US
dc.title Metal-catalyzed cross-coupling reactions with dithiolanes and dithianes en_US
dc.degree.discipline Chemistry en_US
dc.contributor.examiningcommittee Schweizer, Frank (Chemistry) Sorensen, John (Chemistry) Liu, Song (Textile Sciences) en_US
dc.degree.level Master of Science (M.Sc.) en_US
dc.description.note February 2013 en_US


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