Medulloblastoma (MB) is the most common primary malignant pediatric brain tumor. The relationship between stem cell function and invasiveness has not been investigated in MB. We have dissected MB heterogeneity and compared ...

Patients with kidney failure on dialysis are at high risk for cardiovascular disease and premature death in aggregate. Individual patient risk, however, varies widely. Improved ascertainment of individual risk could inform ...

Motor vehicle collisions are the leading cause of injury death for Canadian children, with improper restraint being an important and preventable contributing factor. Children 4-8 years of age are the least likely to be ...

Psoriasiform disorders, are a group of skin diseases characterized by thickened skin (acanthosis). Psoriasis and seborrheic dermatitis, prototypical examples of this disease class, affect up to 4% of the population (Johnson, ...

The number of people diagnosed and living with kidney failure requiring dialysis in Canada has tripled in the last two decades. In center hemodialysis is a thrice-weekly treatment that attempts to remove fluid and toxins ...

Abnormal uterine bleeding (AUB) defines any change in the duration , frequency or flow volume of periods or bleeding between periods. Women experiencing these symptoms are known to have reduced quality of life and experience ...

Rotator cuff tears are a common problem associated with muscle atrophy and fatty infiltration. These changes may be progressive and even irreversible despite successful repair. A deeper understanding of the cellular ...

The objective of this study was to investigate the utility of the methacholine challenge test as a measure of airway hyperresponsiveness, in aiding the clinical diagnosis of asthma. The study comprised 330 high-risk ...

Objective: To assess the use of digital tomosynthesis (DT) as an alternative imaging modality to radiography for the imaging of paediatric sacroiliac (SI) joints. Methods: Three anthropomorphic pelvis phantoms were imaged ...

Cardiovascular disease in pregnancy is the leading cause of maternal morbidity and mortality in North America. Transthoracic echocardiography (TTE) is the most widely used imaging modality for the assessment of cardiovascular ...