Browsing Rady Faculty of Health Sciences by Author "Abrenica, Bernard"
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The transcription factor scleraxis is a critical regulator of cardiac fibroblast phenotype
Bagchi, Rushita A; Roche, Patricia; Aroutiounova, Nina; Espira, Leon; Abrenica, Bernard; Schweitzer, Ronen; Czubryt, Michael P (BMC Biology, 2016-03-17)Background: Resident fibroblasts synthesize the cardiac extracellular matrix, and can undergo phenotype conversion to myofibroblasts to augment matrix production, impairing function and contributing to organ failure. A ...