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Low Prevalence of VRE Gastrointestinal Colonization of Hospitalized Patients in Manitoba Tertiary Care and Community Hospitals
(2000-1-1)
OBJECTIVE: To determine the prevalence of vancomycin-resistant enterococci (VRE) bowel colonization in hospitalized patients in Manitoba who had stool specimens collected for Clostridium difficile toxin and/or culture ...
Mutant Prevention Concentrations of Doripenem and Meropenem Alone and in Combination with Colistin (Polymyxin E), Levofloxacin and Tobramycin in Pseudomonas aeruginosa
(2009-1-1)
BACKGROUND: With a limited number of available antimicrobial
agents to treat Pseudomonas aeruginosa infections, the prevention of
emergence of antimicrobial resistance and its subsequent spread is
critical. In the present ...
Ciprofloxacin or Imipenem Use Correlates with Resistance in Pseudomonas aeruginosa
(1998-1-1)
OBJECTIVE: To investigate the relationship between ciprofloxacin or imipenem use and antimicrobial resistance in Pseudomonas aeruginosa.METHODS: A retrospective review of monthly antimicrobial susceptibility reports for ...
Imipenem and Meropenem: Comparison of In Vitro Activity, Pharmacokinetics, Clinical Trials and Adverse Effects
(1998-1-1)
OBJECTIVE: To compare and contrast imipenem and meropenem in terms of in vitro activity, pharmacokinetics, clinical efficacy and adverse effects.DATA SELECTION: MEDLINE search from 1975 to 1997 and follow-up of references.DATA ...
Antimicrobial Susceptibility of 6685 Organisms Isolated from Canadian Hospitals: CANWARD 2007
(2009-1-1)
BACKGROUND: Antimicrobial resistance is a growing problem in
North American hospitals as well as hospitals worldwide.
OBJECTIVES: To assess the antimicrobial susceptibility patterns of
commonly used agents against the 20 ...
Susceptibility of Community Gram-Negative Urinary Tract Isolates to Mecillinam and Other Oral Agents
(2001-1-1)
OBJECTIVE: To determine the susceptibility of community outpatient Gram-negative urinary tract isolates to mecillinam and other commonly used oral agents.DESIGN AND SETTING: The study was a laboratory-based study of ...
Clinical Practice Guidelines for Hospital-Acquired Pneumonia and Ventilator-Associated Pneumonia in Adults
(2008-1-1)
Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) are important causes of morbidity and mortality, with mortality rates approaching 62%. HAP and VAP are the second most common cause of nosocomial ...
Prevalence of Antimicrobial-Resistant Pathogens in Canadian Hospitals: Results of the Canadian Ward Surveillance Study (CANWARD 2007)
(2009-1-1)
BACKGROUND: Canadian hospitals as well as hospitals worldwide
are increasingly faced with antibiotic-resistant pathogens, including
multidrug-resistant (MDR) strains.
OBJECTIVES: To assess the prevalence of pathogens, ...
Fidaxomicin: A Novel Agent for the Treatment of Clostridium difficile Infection
(2015-1-1)
BACKGROUND: Due to the limitations of existing treatment options for Clostridium difficile infection (CDI), new therapies are needed.OBJECTIVE: To review the available data on fidaxomicin regarding chemistry, mechanisms ...
Antibiotic and Oral Contraceptive Drug Interactions: Is There a Need for Concern?
(1999-1-1)
OBJECTIVE: To assess the clinical significant of antibiotic and oral contraceptive drug interactions.DATA SELECTION: MEDLINE search from 1975 to 1998 (September) inclusive. Search terms ‘antitiobic’, ‘oral contraceptive’ ...