College of Medicine - Master of Physician Assistant Studies Capstone Projects

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Browsing College of Medicine - Master of Physician Assistant Studies Capstone Projects by Subject "Amnisure"

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    A survey designed study on cost effectiveness of Amnisure: Should Amnisure replace Ferning and Nitrazine as the test of choice for diagnosis of rupture of membranes?
    (2015-04) Yang, Lu Ting
    Rupture of membrane (ROM) is most commonly diagnosed clinically with physical examination; however, approximately 20% of women present very subtly, thus, making diagnosis difficult. An accurate diagnosis is important as it will influence subsequent management and care plan. The current diagnostic standard uses ferning and/or nitrazine, which performs at very low cost but with a low specificity value. This is a survey-designed study, information collected are used to estimate cost in introducing Amnisure in a selective fashion and for every patient with query PROM, to inform better decision making when using in triage unit at The Women's Hospital. Methods- From March 14, 2015-April 14 2015, data will be gathered from triage unit in Women’s Hospital including women that presents with query SROM. An assessment by medical staff if an Amnisure kit would have been useful in establishing diagnosis Results- We determined from this study that approximately 25%-37.5% of PROM would benefit from Amnisure use in diagnosis of PROM. The cost of Amnisure per year is $7192.8-$10,789.2 in selective use and $28,171.8 in standard use. Conclusion- Amnisure is an accurate method for diagnosing rupture of fetal membranes with high sensitivity, specificity, negative predictive and positive predictive values. Amnisure also concluded in this study to be cost effective.