<?xml version="1.0" encoding="UTF-8"?>
<front xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.0/xsd/JATS-journalpublishing1.xsd">
	<journal-meta>
		<journal-id journal-id-type="publisher-id">JP</journal-id>
		<journal-title-group>
			<journal-title>Journal of Pregnancy</journal-title>
		</journal-title-group>
		<issn pub-type="epub">2090-2735</issn>
		<issn pub-type="ppub">2090-2727</issn>
		<publisher>
			<publisher-name>Hindawi Publishing Corporation</publisher-name>
		</publisher>
	</journal-meta>
	<article-meta>
		<article-id pub-id-type="other">329618</article-id>
		<article-id pub-id-type="doi">10.1155/2010/329618</article-id>
		<article-id pub-id-type="publisher-id">329618</article-id>
		<article-categories>
			<subj-group subj-group-type="heading">
				<subject>Case Report</subject>
			</subj-group>
		</article-categories>
		<title-group>
			<article-title>Conservative Management of Placenta Accreta in a Multiparous Woman</article-title>
		</title-group>
		<contrib-group>
			<contrib contrib-type="author" id="U84981512" corresp="yes">
				<name>
					<surname>Hunt</surname>
					<given-names>Jennifer C.</given-names>
				</name>
				<email>jen_hunt@shaw.ca</email>
				<xref ref-type="aff" rid="I1"/>
			</contrib>
			<contrib contrib-type="Academic Editor" id="U61273417">
				<name>
					<surname>Prefumo</surname>
					<given-names>Federico</given-names>
				</name>
			</contrib>
		</contrib-group>
		<aff id="I1">
			<addr-line>Department of Obstetrics, Gynecology, and Reproductive Sciences</addr-line>
			<addr-line>University of Manitoba</addr-line>
			<addr-line>Women's Hospital</addr-line>
			<addr-line>Room WS125</addr-line>
			<addr-line>735 Notre Dame Avenue</addr-line>
			<addr-line>Winnipeg, MB</addr-line>
			<country>Canada</country>
			<addr-line>R3E 0L8</addr-line>
			<ext-link ext-link-type="domain-name">umanitoba.ca</ext-link>
		</aff>
		<pub-date pub-type="publication-year">
			<year>2010</year>
		</pub-date>
		<pub-date pub-type="archival-date">
			<day>30</day>
			<month>9</month>
			<year>2010</year>
		</pub-date>
		<volume>2010</volume>
		<history>
			<date date-type="received">
				<day>13</day>
				<month>07</month>
				<year>2010</year>
			</date>
			<date date-type="accepted">
				<day>27</day>
				<month>08</month>
				<year>2010</year>
			</date>
		</history>
		<permissions>
			<copyright-year>2010</copyright-year>
			<copyright-holder>Copyright © 2010 Jennifer C. Hunt.</copyright-holder>
			<license license-type="open-access">
				<license-p>This is an open access article distributed under the <ext-link xlink:href="http://creativecommons.org/licenses/by/3.0/">Creative Commons Attribution License</ext-link>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
			</license>
		</permissions>
		<abstract>
			<p>Placenta accreta refers to any abnormally invasive placental implantation.  Diagnosis is suspected postpartum with failed delivery of a retained placenta. Massive obstetrical hemorrhage is a known complication, often requiring peripartum hysterectomy. We report a case of presumed placenta accreta in a patient following failed manual removal of a retained placenta. We describe an attempt at conservative management with methotrexate in a stable patient desiring future fertility.  Treatment was unsuccessful and led to the development of a disseminated intrauterine infection complicated by a bowel obstruction, requiring both a hysterectomy and small bowel resection.  In hemodynamically stable patients, conservative management of placenta accreta may involve leaving placental tissue <italic>in situ</italic> with subsequent administration of methotrexate.  However, ongoing close observation is required to identify complications.</p>
		</abstract>
		<counts>
			<ref-count count="17"/>
			<page-count count="5"/>
		</counts>
	</article-meta>
</front>
