Measures of Relative Importance 1 for Health-Related Quality of Life

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dc.contributor.authorSajobi, Tolulope
dc.contributor.authorLix, Lisa
dc.contributor.authorClara, Ian
dc.contributor.authorWalker, John
dc.contributor.authorGraff, Lesley A.
dc.contributor.authorRawsthorne, Patricia
dc.contributor.authorMiller, Norine
dc.contributor.authorRogala, Linda
dc.contributor.authorCarr, Rachel
dc.contributor.authorBernstein, Charles N.
dc.date.accessioned2015-05-11T17:48:59Z
dc.date.available2015-05-11T17:48:59Z
dc.date.issued2012-02
dc.description.abstractPURPOSE: In health-related quality of life (HRQOL) studies, data are often collected on multiple domains for two or more groups of study participants. Quantitative measures of relative importance, which are used to rank order the domains based on their ability to discriminate between groups, are an alternative to multiple tests of significance on the group differences. This study describes relative importance measures based on logistic regression (LR) and multivariate analysis of variance (MANOVA) models. METHODS: Relative importance measures are illustrated using data from the Manitoba Inflammatory Bowel Disease (IBD) Cohort Study. Study participants with self-reported active (n = 244) and inactive (n = 105) disease were compared on 12 HRQOL domains from the Inflammatory Bowel Disease Questionnaire (IBDQ) and Medical Outcomes Study 36-item Short-Form (SF-36) Questionnaire. RESULTS: All but two relative importance measures ranked the IBDQ bowel symptoms and emotional health domains as most important. CONCLUSIONS: MANOVA-based importance measures are recommended for multivariate normal data and when group covariances are equal, while LR measures are recommended for non-normal data and when the correlations among the domains are small. Relative importance measures can be used in exploratory studies to identify a small set of domains for further research.en_US
dc.identifier.citationQual Life Res. 2012 Feb;21(1):1-11en_US
dc.identifier.doi10.1007/s11136-011-9914-7
dc.identifier.urihttp://hdl.handle.net/1993/30423
dc.language.isoengen_US
dc.publisherQuality of Life Researchen_US
dc.relation.ispartofseries21(1);1-11
dc.rightsopen accessen_US
dc.subjectHealth Servicesen_US
dc.subjectInflammatory Bowel Diseaseen_US
dc.subjectQuality of lifeen_US
dc.subjectBernsteinen_US
dc.titleMeasures of Relative Importance 1 for Health-Related Quality of Lifeen_US
dc.typeArticleen_US
dc.typeDataseten_US
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