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Please use this identifier to cite or link to this item: http://hdl.handle.net/1993/8618

Title: 2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema
Authors: Bowen, Tom
Cicardi, Marco
Farkas, Henriette
Bork, Konrad
Longhurst, Hilary J
Zuraw, Bruce
Aygoeren-Pursun, Emel
Craig, Timothy
Binkley, Karen
Hebert, Jacques
Ritchie, Bruce
Bouillet, Laurence
Betschel, Stephen
Cogar, Della
Dean, John
Devaraj, Ramachand
Hamed, Azza
Kamra, Palinder
Keith, Paul K
Lacuesta, Gina
Leith, Eric
Lyons, Harriet
Mace, Sean
Mako, Barbara
Neurath, Doris
Poon, Man-Chiu
Rivard, Georges-Etienne
Schellenberg, Robert
Rowan, Dereth
Rowe, Anne
Stark, Donald
Sur, Smeeksha
Tsai, Ellie
Warrington, Richard
Waserman, Susan
Ameratunga, Rohan
Bernstein, Jonathan
Bjorkander, Janne
Brosz, Kristylea
Brosz, John
Bygum, Anette
Caballero, Teresa
Frank, Mike
Fust, George
Harmat, George
Kanani, Amin
Kreuz, Wolfhart
Levi, Marcel
Li, Henry
Martinez-Saguer, Inmaculada
Moldovan, Dumitru
Nagy, Istvan
Nielsen, Erik W
Nordenfelt, Patrik
Reshef, Avner
Rusicke, Eva
Smith-Foltz, Sarah
Spath, Peter
Varga, Lilian
Xiang, Zhi Y
Issue Date: 28-Jul-2010
Citation: Allergy, Asthma & Clinical Immunology. 2010 Jul 28;6(1):24
Abstract: Abstract Background We published the Canadian 2003 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema (HAE; C1 inhibitor [C1-INH] deficiency) and updated this as Hereditary angioedema: a current state-of-the-art review: Canadian Hungarian 2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema. Objective To update the International Consensus Algorithm for the Diagnosis, Therapy and Management of Hereditary Angioedema (circa 2010). Methods The Canadian Hereditary Angioedema Network (CHAEN)/Réseau Canadien d'angioédème héréditaire (RCAH) http://www.haecanada.com and cosponsors University of Calgary and the Canadian Society of Allergy and Clinical Immunology (with an unrestricted educational grant from CSL Behring) held our third Conference May 15th to 16th, 2010 in Toronto Canada to update our consensus approach. The Consensus document was reviewed at the meeting and then circulated for review. Results This manuscript is the 2010 International Consensus Algorithm for the Diagnosis, Therapy and Management of Hereditary Angioedema that resulted from that conference. Conclusions Consensus approach is only an interim guide to a complex disorder such as HAE and should be replaced as soon as possible with large phase III and IV clinical trials, meta analyses, and using data base registry validation of approaches including quality of life and cost benefit analyses, followed by large head-to-head clinical trials and then evidence-based guidelines and standards for HAE disease management.
URI: http://hdl.handle.net/1993/8618
DOI: http://dx.doi.org/10.1186/1710-1492-6-24
Type: Journal Article
Appears in Collection(s):Research Publications

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