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Please use this identifier to cite or link to this item: http://hdl.handle.net/1993/8612

Title: Immunocompetence in young and old laying hens in response to dietary folic acid and Escherichia coli lipopolysaccharide challenge
Authors: Munyaka, Peris Mumbi
Supervisor: Rodriguez-Lecompte, J.C. (Animal Science)
Examining Committee: House, J.D (Animal Science and Human Nutrition) Nyachoti, C.M (Animal Science) O, Karmin (Animal Science and Physiology) Holley, Rick (Food Science)
Graduation Date: October 2012
Keywords: folic acid
lipopolysaccharide
immune response
laying hen
Age
Issue Date: 6-Sep-2012
Abstract: We investigated the effects of dietary folic acid and age, on immunological parameters in laying hens challenged with LPS. 48 Shaver White hens at different ages were fed 2 wheat-soybean based diets with 0 or 4 mg supplemental FA per kg of diet for 8 wk. 6 hens from each dietary treatment were injected with 8 mg/kg body weight of LPS or saline and observed for 4 h. A few diet X challenge interaction were observed in young hens, whereas FA and LPS independently influenced a number of parameters. In older hens, there were very few diet X challenge interactions as well as effects of FA, whereas LPS affected several parameters. In conclusion, dietary FA influenced some immune responses in younger hens, but no such effects were observed in older hens. FA may modulate immune responses in laying hens under acute LPS challenge which could be tissue and age dependent.
URI: http://hdl.handle.net/1993/8612
Appears in Collection(s):FGS - Electronic Theses & Dissertations (Public)

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