Diarrhea and colonic ulcers of unusual etiology
Loading...
Date
2012-04-25
Authors
Keynan, Yoav
Cantor, Michael J.
Grynspan, David
Lategan, Belinda
Orr, Pamela H.
Journal Title
Journal ISSN
Volume Title
Publisher
OMICS
Abstract
The present report describes a case of chronic diarrhea with several ulcers in the ascending colon in a 47-year old
woman who immigrated to Canada from the Philippines. A biopsy from affected colon revealed caseating
granulomas and culture grew mycobacterium avium subspecies. Polymerase chain reaction from the colonic biopsy
specimen confirmed the presence of mycobacterium avium subspecies that was subsequently identified by hsp65
sequence to be mycobacterium avium hominissuis (MAH). Anti-mycobacterial therapy was started but discontinued
by the patient. After 6 months a repeat colonoscopy was macroscopically normal and no granulomas could be seen
on biopsies taken from normal appearing colonic tissue. The epidemiological features, host-range and laboratory
identification of this unusual organism are discussed.
Description
Keywords
Mycobacterium avium, Mycobacterium avium hominissuis, Granulomatous colitis
Citation
Keynan Y, Cantor MJ, Grynspan D, Lategan B, Orr PH (2012) Diarrhea and Colonic Ulcers of Unusual Etiology. Mycobac Dis 2:112.